IRAK1 and IRAK4 as emerging therapeutic targets in hematologic malignancies
J Bennett, DT Starczynowski - Current Opinion in Hematology, 2022 - journals.lww.com
IRAK-targeted therapies that have matriculated to early phase trials are yielding promising
preliminary results. However, studies of IRAK kinase signaling continue to defy conventional …
preliminary results. However, studies of IRAK kinase signaling continue to defy conventional …
Circulating tumor DNA detection: A potential tool for colorectal cancer management
H Li, C Jing, J Wu, J Ni, H Sha, X Xu… - Oncology …, 2019 - spandidos-publications.com
Colorectal cancer (CRC) is frequently diagnosed at an advanced stage of the disease, the
pathogenesis of which is influenced by genetic and epigenetic events. Circulating tumor …
pathogenesis of which is influenced by genetic and epigenetic events. Circulating tumor …
Peptides and combination of peptides for use in immunotherapy against small cell lung cancer and other cancers
M Andrea, T Weinschenk, V Goldfinger… - US Patent …, 2019 - Google Patents
The present invention relates to peptides, proteins, nucleic acids and cells for use in
immunotherapeutic methods. In particular, the present invention relates to the immuno …
immunotherapeutic methods. In particular, the present invention relates to the immuno …
Peptides and combination of peptides for use in immunotherapy against small cell lung cancer and other cancers
A Mahr, T Weinschenk, V Goldfinger, O Schoor… - 2018 - Google Patents
ZRKFYGHZFMAOKI-QMGMOQQFSA-N tgfbeta Chemical compound C ([C@ H](NC (=
O)[C@ H](C (C) C) NC (= O) CNC (= O)[C@ H](CCC (O)= O) NC (= O)[C@ H](CCCNC (N) …
O)[C@ H](C (C) C) NC (= O) CNC (= O)[C@ H](CCC (O)= O) NC (= O)[C@ H](CCCNC (N) …
DDX1 is a prognostic biomarker and correlates with immune infiltrations in hepatocellular carcinoma
M Yuan, J Xu, S Cao, S Sun - BMC immunology, 2022 - Springer
Hepatocellular carcinoma (HCC) is one of the leading lethal malignant tumors worldwide.
DEAD-box (DDX) family helicases are implicated in numerous human cancers. However …
DEAD-box (DDX) family helicases are implicated in numerous human cancers. However …
Integrative multi-platform meta-analysis of gene expression profiles in pancreatic ductal adenocarcinoma patients for identifying novel diagnostic biomarkers
A Irigoyen, C Jimenez-Luna, M Benavides, O Caba… - PLoS …, 2018 - journals.plos.org
Applying differentially expressed genes (DEGs) to identify feasible biomarkers in diseases
can be a hard task when working with heterogeneous datasets. Expression data are strongly …
can be a hard task when working with heterogeneous datasets. Expression data are strongly …
The mechanistic, diagnostic and therapeutic novel nucleic acids for hepatocellular carcinoma emerging in past score years
Abstract Despite The Central Dogma states the destiny of gene as 'DNA makes RNA and
RNA makes protein', the nucleic acids not only store and transmit genetic information but …
RNA makes protein', the nucleic acids not only store and transmit genetic information but …
[HTML][HTML] The potential of liquid biopsies in gastrointestinal cancer
C Wu, J Zhang, H Li, W Xu, X Zhang - Clinical Biochemistry, 2020 - Elsevier
Background Liquid biopsy is a novel approach for cancer diagnosis, the value of which in
human gastrointestinal (GI) cancer has been confirmed by the previous studies. This article …
human gastrointestinal (GI) cancer has been confirmed by the previous studies. This article …
Retracted: IRAK3 gene silencing prevents cardiac rupture and ventricular remodeling through negative regulation of the NF‐κB signaling pathway in a mouse model …
ZW Ge, BC Wang, JL Hu, JJ Sun… - Journal of cellular …, 2019 - Wiley Online Library
Cardiac rupture and ventricular remodeling are recognized as the severe complications and
major risk factors of acute myocardial infarction (AMI). This study aims to evaluate the …
major risk factors of acute myocardial infarction (AMI). This study aims to evaluate the …
IL-1 receptor-associated kinase family proteins: An overview of their role in liver disease
Z Wang, S Gao, X Gou, F Qiu, Q Feng - European Journal of Pharmacology, 2024 - Elsevier
Abstract 1 The interleukin-1 receptor-associated kinase (IRAK) family is a group of serine-
threonine kinases that regulates various cellular processes via toll-like receptor …
threonine kinases that regulates various cellular processes via toll-like receptor …