DNA methylation analysis: choosing the right method
S Kurdyukov, M Bullock - Biology, 2016 - mdpi.com
In the burgeoning field of epigenetics, there are several methods available to determine the
methylation status of DNA samples. However, choosing the method that is best suited to …
methylation status of DNA samples. However, choosing the method that is best suited to …
Molecular biomarkers in acute myeloid leukemia
Acute myeloid leukemia (AML) is the most common acute leukemia in adults. The
pathophysiology of this disease is just beginning to be understood at the cellular and …
pathophysiology of this disease is just beginning to be understood at the cellular and …
DNA methylation validation methods: a coherent review with practical comparison
Š Šestáková, C Šálek, H Remešová - Biological procedures online, 2019 - Springer
Here, we present a practical overview of four commonly used validation methods for DNA
methylation assessment: methylation specific restriction endonucleases (MSRE) analysis …
methylation assessment: methylation specific restriction endonucleases (MSRE) analysis …
Properties and application of cell-free DNA as a clinical biomarker
FS de Miranda, VG Barauna, L Dos Santos… - International Journal of …, 2021 - mdpi.com
Biomarkers are valuable tools in clinical practice. In 2001, the National Institutes of Health
(NIH) standardized the definition of a biomarker as a characteristic that is objectively …
(NIH) standardized the definition of a biomarker as a characteristic that is objectively …
MHC and Evolution in Teleosts
U Grimholt - Biology, 2016 - mdpi.com
Major histocompatibility complex (MHC) molecules are key players in initiating immune
responses towards invading pathogens. Both MHC class I and class II genes are present in …
responses towards invading pathogens. Both MHC class I and class II genes are present in …
Blood DNA methylation as a potential biomarker of dementia: a systematic review
Dementia is a major public health issue with rising prevalence rates, but many individuals
remain undiagnosed. Accurate and timely diagnosis is key for the optimal targeting of …
remain undiagnosed. Accurate and timely diagnosis is key for the optimal targeting of …
The epigenetic landscape of circulating tumour cells
Cancer metastasis is the main reason for the high mortality in patients, contributing to 90% of
cancer-related deaths. Biomarkers for early detection and therapeutic monitoring are …
cancer-related deaths. Biomarkers for early detection and therapeutic monitoring are …
Epigenetics and inflammatory markers: a systematic review of the current evidence
V Gonzalez-Jaramillo… - International journal …, 2019 - Wiley Online Library
Epigenetic mechanisms have been suggested to play a role in the genetic regulation of
pathways related to inflammation. Therefore, we aimed to systematically review studies …
pathways related to inflammation. Therefore, we aimed to systematically review studies …
Epigenome‐wide association studies in asthma: a systematic review
Objective Asthma is a common chronic respiratory airway disease influenced by
environmental factors and possibly their interaction with the human genome causing …
environmental factors and possibly their interaction with the human genome causing …
Variation in DNA methylation of human blood over a 1-year period using the Illumina MethylationEPIC array
Assessing DNA methylation profiles in human blood has become a major focus of
epidemiologic inquiry. Understanding variability in CpG-specific DNA methylation over …
epidemiologic inquiry. Understanding variability in CpG-specific DNA methylation over …