Cancer stem cells (CSCs) are a population of self-renewal cells with high tumorigenic
potency. CSCs can adopt easily with changes in the nearby milieu, and are more resistant to …

Glioblastoma (GBM) is the most lethal type of primary brain cancer. Standard care using
chemo-and radio-therapy modestly increases the overall survival of patients; however …

Long noncoding RNAs (lncRNAs) are involved in glioma initiation and progression. Glioma
stem cells (GSCs) are essential for tumor initiation, maintenance, and therapeutic resistance …

The acquisition of cancer cell resistance to conventional chemotherapeutics is considered
the major driver of treatment failure and disease recurrence in most solid and hematological …

Glioblastoma (GBM) is the most common and aggressive primary brain tumor and is nearly
universally fatal. Targeted therapy and immunotherapy have had limited success in GBM …

Glioblastoma is the most aggressive malignant tumor of the central nervous system with a
low survival rate. The difficulty of obtaining this tumor material represents a major limitation …

A growing body of evidence suggests that long-chain non-coding RNA (lncRNA) plays an
important role in the malignant biological behavior and drug resistance of glioblastoma …

Solid tumors can be divided into benign solid tumors and solid malignant tumors in the
academic community, among which malignant solid tumors are called cancers. Cancer is …

Glioma is the most common malignant brain tumor that develops in the glial tissue. Several
studies have identified that glioma cancer stem cells (GCSCs) play important roles in tumor …

Background LncRNAs have been shown to play essential roles in cancer therapeutic
response. However, the detailed mechanism of lncRNAs in temozolomide (TMZ) resistance …