[HTML][HTML] Intracranial Aneurysms and Genetics: An Extensive Overview of Genomic Variations, Underlying Molecular Dynamics, Inflammatory Indicators, and Forward …

C Toader, L Eva, BG Bratu, RA Covache-Busuioc… - Brain Sciences, 2023 - mdpi.com
This review initiates by outlining the clinical relevance of IA, underlining the pressing need to
comprehend its foundational elements. We delve into the assorted risk factors tied to IA …

[HTML][HTML] Aspirin treatment for unruptured intracranial aneurysms: Focusing on its anti-inflammatory role

Y Feng, H Zhang, S Dai, X Li - Heliyon, 2024 - cell.com
Intracranial aneurysms (IAs), as a common cerebrovascular disease, claims a worldwide
morbidity rate of 3.2%. Inflammation, pivotal in the pathogenesis of IAs, influences their …

Association of calcium channel blockers with lower incidence of intracranial aneurysm rupture and growth in hypertensive patients

Q Liu, J Li, Y Zhang, X Leng, M Mossa-Basha… - Journal of …, 2023 - thejns.org
OBJECTIVE Calcium channel blockers (CCBs) are antihypertensive agents with potential
vascular protection effects. This study investigated whether CCB usage was associated with …

Can β-blockers prevent intracranial aneurysm rupture?: insights from Computational Fluid Dynamics analysis

KM Kliś, RM Krzyżewski, BM Kwinta… - Cardiovascular …, 2024 - academic.oup.com
Aims Hypertension is a risk factor for intracranial aneurysm rupture. We analysed whether
the intake of drugs from specific classes of anti-hypertensive medications affects …

[HTML][HTML] Are South African wild foods the answer to rising rates of cardiovascular disease?

NJ Sadgrove - Diversity, 2022 - mdpi.com
The rising burden of cardiovascular disease in South Africa gives impetus to managerial
changes, particularly to the available foods in the market. Since there are many …

[HTML][HTML] A web-based dynamic nomogram for rupture risk of posterior communicating artery aneurysms utilizing clinical, morphological, and hemodynamic …

H Wei, W Han, Q Tian, K Yao, P He, J Wang… - Frontiers in …, 2022 - frontiersin.org
Background Predicting rupture risk is important for aneurysm management. This research
aimed to develop and validate a nomogram model to forecast the rupture risk of posterior …

[HTML][HTML] Impact of premorbid hypertension and renin-angiotensin-aldosterone system inhibitors on the severity of aneurysmal subarachnoid haemorrhage: a …

P Zhong, Z Lu, Z Li, T Li, Q Lan, J Liu, S Chen… - Stroke and Vascular …, 2024 - svn.bmj.com
Background Hypertension is widely acknowledged as a significant contributory factor to the
heightened risk of intracranial aneurysm rupture. Nevertheless, the impact of hypertension …

[HTML][HTML] Pharmaceutical Modulation of Intracranial Aneurysm Development and Rupture

A Crane, RM Shanahan, JS Hudson… - Journal of Clinical …, 2024 - mdpi.com
Management of intracranial aneurysms (IAs) is determined by patient age, risk of rupture,
and comorbid conditions. While endovascular and microsurgical interventions offer solutions …

Genetically determined blood pressure, antihypertensive medications, and risk of intracranial aneurysms and aneurysmal subarachnoid hemorrhage: A Mendelian …

H Liu, H Zuo, O Johanna, R Zhao… - European Stroke …, 2024 - journals.sagepub.com
Introduction: Observational studies suggest that different classes of antihypertensive drugs
may have different effects on the occurrence of intracranial aneurysms (IA) and …

[HTML][HTML] Association between psychiatric disorders and intracranial aneurysms: evidence from Mendelian randomization analysis

S Bao, Z Xing, S He, X Hu, J Yang, B Zhou - Frontiers in Neurology, 2024 - frontiersin.org
Objective Several studies have explored the relationship between intracranial aneurysms
and psychiatric disorders; nevertheless, the causal connection remains ambiguous. This …