Background Hyperuricemia has been reported to be associated with chronic kidney disease
(CKD). However whether an elevated serum uric acid level is an independent risk factor for …

Objective The role of serum uric acid as an independent risk factor for cardiovascular
disease remains unclear, although hyperuricemia is associated with cardiovascular disease …

Context Patients with chronic disabling gout refractory to conventional urate-lowering
therapy need timely treatment to control disease manifestations related to tissue urate crystal …

Lanthanide (such as Tb and Eu) metal–organic frameworks (MOFs) have been widely used
in fluorescent probes because of their multiple coordination modes and brilliant …

Uric acid (UA) detection is essential in diagnosis of arthritis, preeclampsia, renal disorder,
and cardiovascular diseases, but it is very challenging to realize the required wide detection …

Introduction The purpose of this study was to compare urate-lowering (UL) efficacy and
safety of daily febuxostat and allopurinol in subjects with gout and serum urate (sUA)≥ 8.0 …

Objective To assess the association between hyperuricemia and risk of stroke incidence and
mortality because hyperuricemia is hypothesized to be a risk factor for stroke and other …

Uric acid is the end product of purine metabolism in humans and great apes, which have lost
hepatic uricase activity, leading to uniquely high serum uric acid concentrations (200–500 …

Hyperuricemia is a significant factor in a variety of diseases, including gout and
cardiovascular diseases. Although renal excretion largely determines plasma urate …

Uric acid (UA) is a risk factor for endothelial dysfunction, a process in which inflammation
may play an important role. UA increases high mobility group box chromosomal protein 1 …