Flow-induced, inflammation-mediated arterial wall remodeling in the formation and progression of intracranial aneurysms
OBJECTIVE Unruptured intracranial aneurysms (UIAs) are relatively common lesions that
may cause devastating intracranial hemorrhage, thus producing considerable suffering and …
may cause devastating intracranial hemorrhage, thus producing considerable suffering and …
The biophysical role of hemodynamics in the pathogenesis of cerebral aneurysm formation and rupture
The pathogenesis of intracranial aneurysms remains complex and multifactorial. While
vascular, genetic, and epidemiological factors play a role, nascent aneurysm formation is …
vascular, genetic, and epidemiological factors play a role, nascent aneurysm formation is …
Prostaglandin E2–EP2–NF-κB signaling in macrophages as a potential therapeutic target for intracranial aneurysms
Intracranial aneurysms are common but are generally untreated, and their rupture can lead
to subarachnoid hemorrhage. Because of the poor prognosis associated with subarachnoid …
to subarachnoid hemorrhage. Because of the poor prognosis associated with subarachnoid …
Vessel wall enhancement in unruptured intracranial aneurysms: an indicator for higher risk of rupture? High-resolution MR imaging and correlated histologic findings
N Larsen, C Von Der Brelie, D Trick… - American Journal …, 2018 - Am Soc Neuroradiology
BACKGROUND AND PURPOSE: Recent studies have suggested that wall enhancement of
unruptured intracranial aneurysms in high-resolution MR imaging might serve as an imaging …
unruptured intracranial aneurysms in high-resolution MR imaging might serve as an imaging …
What does computational fluid dynamics tell us about intracranial aneurysms? A meta-analysis and critical review
Despite the plethora of published studies on intracranial aneurysms (IAs) hemodynamic
using computational fluid dynamics (CFD), limited progress has been made towards …
using computational fluid dynamics (CFD), limited progress has been made towards …
Local hemodynamic conditions associated with focal changes in the intracranial aneurysm wall
BACKGROUND AND PURPOSE: Aneurysm hemodynamics has been associated with wall
histology and inflammation. We investigated associations between local hemodynamics and …
histology and inflammation. We investigated associations between local hemodynamics and …
Role of hemodynamics in initiation/growth of intracranial aneurysms
MR Diagbouga, S Morel, P Bijlenga… - European journal of …, 2018 - Wiley Online Library
Background Intracranial aneurysm (IA) is a disease of the vascular wall resulting in
abnormal enlargement of the vessel lumen. It is a common pathology with a prevalence of …
abnormal enlargement of the vessel lumen. It is a common pathology with a prevalence of …
Risk factors for hemorrhage of brain arteriovenous malformation
SS Shaligram, E Winkler, D Cooke… - CNS neuroscience & …, 2019 - Wiley Online Library
Patients with brain arteriovenous malformation (bAVM) are at risk of intracranial hemorrhage
(ICH). Overall, bAVM accounts for 25% of hemorrhagic strokes in adults< 50 years of age …
(ICH). Overall, bAVM accounts for 25% of hemorrhagic strokes in adults< 50 years of age …
[HTML][HTML] Imaging modalities for intracranial aneurysm: more than meets the eye
C Maupu, H Lebas, Y Boulaftali - Frontiers in Cardiovascular Medicine, 2022 - frontiersin.org
Intracranial aneurysms (IA) are often asymptomatic and have a prevalence of 3 to 5% in the
adult population. The risk of IA rupture is low, however when it occurs half of the patients …
adult population. The risk of IA rupture is low, however when it occurs half of the patients …
[HTML][HTML] Fluid–structure interaction (FSI) simulation for studying the impact of atherosclerosis on hemodynamics, arterial tissue remodeling, and initiation risk of …
The biomechanical and hemodynamic effects of atherosclerosis on the initiation of
intracranial aneurysms (IA) are not yet clearly discovered. Also, studies for the observation of …
intracranial aneurysms (IA) are not yet clearly discovered. Also, studies for the observation of …