Endothelial cells (ECs) respond to flow stress via a variety of mechanisms, leading to
various intracellular responses that can modulate the vessel wall and lead to diseases if the …

Saccular intracranial aneurysm (sIA) rupture leads to subarachnoid haemorrhage and is
preceded by chronic inflammation and atherosclerotic changes of the sIA wall. Increased …

Abstract Background and Purpose Hemodynamics play a driving role in the life cycle of
brain aneurysms from initiation through growth until eventual rupture. The specific factors …

Introduction Wall shear stress (WSS) is associated with the growth and rupture of an
intracranial aneurysm. To reveal their underlying connections, many image-based …

Background Computational fluid dynamics (CFD) blood flow predictions in intracranial
aneurysms promise great potential to reveal patient-specific flow structures. Since the …

Background Blebs are rupture risk factors in intracranial aneurysms (IAs), but their
prevalence, distribution, and associations with clinical factors as well as their causes and …

Background To date, it remains difficult for clinicians to reliably assess the disease status of
intracranial aneurysms. As an aneurysm's 3D shape is strongly dependent on the underlying …

Introduction Connecting local hemodynamics, biomechanics, and tissue properties in
cerebral aneurysms is important for understanding the processes of wall degeneration and …

OBJECTIVE Degenerative cerebral aneurysm walls are associated with aneurysm rupture
and subarachnoid hemorrhage. Thin-walled regions (TWRs) represent fragile areas that …

The lattice Boltzmann method (LBM) has recently emerged as an efficient alternative to
classical Navier-Stokes solvers. This is particularly true for hemodynamics in complex …