Unveiling the future of metabolic medicine: omics technologies driving personalized solutions for precision treatment of metabolic disorders
Metabolic disorders are increasingly prevalent worldwide, leading to high rates of morbidity
and mortality. The variety of metabolic illnesses can be addressed through personalized …
and mortality. The variety of metabolic illnesses can be addressed through personalized …
Protein neddylation and its role in health and diseases
NEDD8 (Neural precursor cell expressed developmentally downregulated protein 8) is an
ubiquitin-like protein that is covalently attached to a lysine residue of a protein substrate …
ubiquitin-like protein that is covalently attached to a lysine residue of a protein substrate …
Emerging epigenetic insights into aging mechanisms and interventions
Epigenetic dysregulation emerges as a critical hallmark and driving force of aging. Although
still an evolving field with much to explore, it has rapidly gained significance by providing …
still an evolving field with much to explore, it has rapidly gained significance by providing …
360-degree perspectives on obesity
M Cuciureanu, CC Caratașu, L Gabrielian… - Medicina, 2023 - mdpi.com
Alarming statistics show that the number of people affected by excessive weight has
surpassed 2 billion, representing approximately 30% of the world's population. The aim of …
surpassed 2 billion, representing approximately 30% of the world's population. The aim of …
Cold exposure protects against medial arterial calcification development via autophagy
FXZ Li, JJ Liu, F Xu, SK Shan, MH Zheng… - Journal of …, 2023 - Springer
Medial arterial calcification (MAC), a systemic vascular disease different from
atherosclerosis, is associated with an increased incidence of cardiovascular events. Several …
atherosclerosis, is associated with an increased incidence of cardiovascular events. Several …
The Transcription Factor HOXA5: Novel Insights into Metabolic Diseases and Adipose Tissue Dysfunction
The transcription factor HOXA5, from the HOX gene family, has long been studied due to its
critical role in physiological activities in normal cells, such as organ development and body …
critical role in physiological activities in normal cells, such as organ development and body …
Metabolic memory: mechanisms and diseases
H Dong, Y Sun, L Nie, A Cui, P Zhao… - Signal transduction and …, 2024 - nature.com
Metabolic diseases and their complications impose health and economic burdens
worldwide. Evidence from past experimental studies and clinical trials suggests our body …
worldwide. Evidence from past experimental studies and clinical trials suggests our body …
Epigenetic regulations of cellular senescence in osteoporosis
S Huo, X Tang, W Chen, D Gan, H Guo, Q Yao… - Ageing Research …, 2024 - Elsevier
Osteoporosis (OP) is a prevalent age-related disease that is characterized by a decrease in
bone mineral density (BMD) and systemic bone microarchitectural disorders. With age …
bone mineral density (BMD) and systemic bone microarchitectural disorders. With age …
The role of epigenetic control of mitochondrial (Dys) Function in MASLD onset and progression
V Caputo, G Tarantino, SJ Santini, G Fracassi… - Nutrients, 2023 - mdpi.com
Metabolic dysfunction-associated steatotic fatty liver disease (MASLD), a novel definition for
NAFLD, represents one of the most common causes of liver disease, and its incidence is …
NAFLD, represents one of the most common causes of liver disease, and its incidence is …
Interplay between gut microbiome, host genetic and epigenetic modifications in MASLD and MASLD-related hepatocellular carcinoma
Metabolic dysfunction-associated steatotic liver disease (MASLD) encompasses a wide
spectrum of liver injuries, ranging from hepatic steatosis, metabolic dysfunction-associated …
spectrum of liver injuries, ranging from hepatic steatosis, metabolic dysfunction-associated …