We critically review potential involvement of trimethylamine N-oxide (TMAO) as a link
between diet, the gut microbiota and CVD. Generated primarily from dietary choline and …

Osmolytes are naturally occurring small molecular weight organic molecules, which are
accumulated in large amounts in all life forms to maintain the stability of cellular proteins and …

Background: Chronic kidney disease (CKD) is a renal disorder characterized by the
accumulation of uremic toxins with limited strategies to reduce their concentrations. A large …

Abstract Purpose of Review Trimethylamine N-oxide (TMAO) is a gut microbiota-dependent
metabolite produced from choline and phosphatidylcholine. Trimethylamine N-oxide was …

The gut microbiota and its metabolites have become a hotspot of recent research.
Trimethylamine N-oxide (TMAO) metabolized by the gut microbiota is closely related to …

Abstract Background and Aims Trimethylamine‐N‐oxide (TMAO), a gut microbiota‐liver
metabolite, has been associated with cardiometabolic disease. However, whether TMAO is …

Aims Little is known about associations of trimethylamine N-oxide (TMAO), a novel gut
microbiota-generated metabolite of dietary phosphatidylcholine and carnitine, and its …

Background and Purpose Chronic kidney disease (CKD) is a global public health problem
and one of the leading causes of all‐cause mortality. However, the pathogenic mechanisms …

Since elevated serum levels of trimethylamine N-oxide (TMAO) were first associated with
increased risk of cardiovascular disease (CVD), TMAO research among chronic diseases …

A large number of different microbial species populates intestine. Extensive research has
studied the entire microbial population and their genes (microbiome) by using …