Trimethylamine N-oxide and the reverse cholesterol transport in cardiovascular disease: a cross-sectional study

L Bordoni, JJ Samulak, AK Sawicka… - Scientific Reports, 2020 - nature.com
The early atherosclerotic lesions develop by the accumulation of arterial foam cells derived
mainly from cholesterol-loaded macrophages. Therefore, cholesterol and cholesteryl ester …

Are we what we eat? The moral imperative of the medical profession to promote plant-based nutrition

SC Hull, J Charles, AL Caplan - The American Journal of Cardiology, 2023 - Elsevier
The typical Western diet, high in processed and animal-based foods, is nutritionally and
ethically problematic. Beyond the well-documented cruelty to animals that characterizes the …

Association of urinary and plasma levels of trimethylamine N-oxide (TMAO) with foods

M Lombardo, G Aulisa, D Marcon, G Rizzo… - Nutrients, 2021 - mdpi.com
Introduction: Trimethylamine N-oxide (TMAO) may play a key mediator role in the
relationship between the diet, gut microbiota and cardiovascular diseases, particularly in …

Gut microbial metabolite TMAO portends prognosis in acute ischemic stroke

J Zhang, L Wang, J Cai, A Lei, C Liu, R Lin, L Jia… - Journal of …, 2021 - Elsevier
Background Over the recent years, the role of trimethylamine N-oxide (TMAO) as a gut-
derived metabolite mediating cardiovascular disease pathogenesis has been under …

Gut microbiota-dependent trimethylamine N-oxide and all-cause mortality: findings from an updated systematic review and meta-analysis

MA Farhangi - Nutrition, 2020 - Elsevier
The gut microbiota-derived metabolite trimethylamine N-oxide (TMAO) has been regarded
as one of the potent risk factors for cardiovascular events and diabetes. In the current meta …

Gut microbiota–associated trimethylamine N‐oxide and increased cardiometabolic risk in adults: a systematic review and dose-response meta-analysis

M Abbasalizad Farhangi, M Vajdi - Nutrition Reviews, 2021 - academic.oup.com
Context Several studies suggest a relationship between trimethylamine N-oxide (TMAO)
concentrations and increased cardiometabolic risk, but findings are controversial. Objective …

Association of trimethylamine N-oxide and metabolites with mortality in older adults

AM Fretts, SL Hazen, P Jensen, M Budoff… - JAMA network …, 2022 - jamanetwork.com
Importance Little is known about the association of trimethylamineN-oxide (TMAO), a novel
plasma metabolite derived from L-carnitine and phosphatidylcholine, and related …

High betaine, a trimethylamine N-oxide related metabolite, is prospectively associated with low future risk of type 2 diabetes mellitus in the PREVEND study

E Garcia, MCJ Osté, DW Bennett, EJ Jeyarajah… - Journal of Clinical …, 2019 - mdpi.com
Background: Gut microbiota-related metabolites, trimethylamine-N-oxide (TMAO), choline,
and betaine, have been shown to be associated with cardiovascular disease (CVD) risk …

Consumption of fish in chronic kidney disease–A matter of depth

D Mafra, JA Kemp, VO Leal, L Cardozo… - Molecular Nutrition & …, 2023 - Wiley Online Library
Fish is an excellent source of ω‐3 polyunsaturated fatty acids (PUFAs), amino acids,
collagen, vitamins, and iodine and its intake is associated with health benefits, mainly …

Short chain fatty acids and methylamines produced by gut microbiota as mediators and markers in the circulatory system

M Onyszkiewicz, K Jaworska… - … biology and medicine, 2020 - journals.sagepub.com
Ample evidence suggests that gut microbiota-derived products affect the circulatory system
functions. For instance, short chain fatty acids, that are the products of dietary fiber bacterial …