Darm-Herz-Achse
H Bartolomaeus, V McParland, N Wilck - Herz, 2020 - Springer
Zusammenfassung Die Betrachtung des Menschen als einen Holobionten, bestehend aus
eukaryotischen Wirtszellen und assoziierten prokaryotischen Lebewesen, hat eine neue …
eukaryotischen Wirtszellen und assoziierten prokaryotischen Lebewesen, hat eine neue …
Plasma Concentrations of Trimethylamine-N-Oxide, Choline, and Betaine in Patients With Moderate to Advanced Chronic Kidney Disease and Their Relation to …
R Obeid, H Awwad, GH Heine, IE Emrich, D Fliser… - Journal of Renal …, 2024 - Elsevier
Objectives Trimethylamine N-oxide (TMAO) is a gut bacteria-mediated liver metabolite of
dietary betaine, choline, and carnitine, which is excreted by glomerular filtration. We studied …
dietary betaine, choline, and carnitine, which is excreted by glomerular filtration. We studied …
Enzymatically produced trimethylamine N-oxide: Conserving it or eliminating it
Trimethylamine N-Oxide (TMAO) is the product of the monooxygenation reaction catalyzed
by a drug-metabolizing enzyme, human flavin-containing monooxygenase 3 (hFMO3), and …
by a drug-metabolizing enzyme, human flavin-containing monooxygenase 3 (hFMO3), and …
Jiangtang Decoction Ameliorates Diabetic Kidney Disease Through the Modulation of the Gut Microbiota
J Hong, T Fu, W Liu, Y Du, J Bu, G Wei… - Diabetes, Metabolic …, 2023 - Taylor & Francis
Purpose This study aimed to elucidate the impact of Jiangtang decoction (JTD) on diabetic
kidney disease (DKD) and its association with alterations in the gut microbiota. Methods …
kidney disease (DKD) and its association with alterations in the gut microbiota. Methods …
Evidence of a causal and modifiable relationship between kidney function and circulating trimethylamine N-oxide with implications for heart and kidney disorders
P Andrikopoulos, J Aron-Wisnewsky, R Chakaroun… - medRxiv, 2022 - medrxiv.org
Objectives The host-microbiota co-metabolite trimethylamine N-oxide (TMAO) is linked to
increased thrombotic and cardiovascular risks. Here we, sought to i) characterize which host …
increased thrombotic and cardiovascular risks. Here we, sought to i) characterize which host …
Plasma carnitine, choline, γ-butyrobetaine, and trimethylamine-N-oxide, but not zonulin, are reduced in overweight/obese patients with pre/diabetes or impaired …
Background and aims Zonulin, carnitine, choline, γ-butyrobetaine (γ-BB), and trimethylamine-
N-oxide (TMAO) are intricately involved in metabolic anomalies and type 2 diabetes mellitus …
N-oxide (TMAO) are intricately involved in metabolic anomalies and type 2 diabetes mellitus …
Circulating trimethylamine N‐oxide levels do not predict 10‐year survival in patients with or without coronary heart disease
EØ Bjørnestad, I Dhar, GFT Svingen… - Journal of Internal …, 2022 - Wiley Online Library
Abstract Background Trimethylamine N‐oxide (TMAO) is an amine oxide generated by gut
microbial metabolism. TMAO may contribute to atherothrombosis and systemic inflammation …
microbial metabolism. TMAO may contribute to atherothrombosis and systemic inflammation …
Gut Microbiome in Dyslipidemia and Atherosclerosis
A Puetz, BA Kappel - Gut Microbiome, Microbial Metabolites and …, 2023 - Springer
Classical risk factors for cardiovascular disease, such as dyslipidemia, arterial hypertension,
obesity, diabetes mellitus, smoking, and genetic predisposition, are well-studied, and their …
obesity, diabetes mellitus, smoking, and genetic predisposition, are well-studied, and their …
Cardiovascular metabolomics
Metabolites are the intermediate outcomes of a number of physiological processes. They are
the most proximal reporters of any disease status or phenotype, and are therefore useful for …
the most proximal reporters of any disease status or phenotype, and are therefore useful for …
老年糖尿病肾病患者肠道菌群失调的研究进展
杜菲， 李英 - 临床荟萃, 2022 - huicui.hebmu.edu.cn
近年来, 随着生活习惯的改变及人口老龄化进程的加快, 我国老年糖尿病患者数量逐渐增多.
在老年糖尿病患者中, 糖尿病肾病(diabetic nephropathy, DN) 的发病率极高 …
在老年糖尿病患者中, 糖尿病肾病(diabetic nephropathy, DN) 的发病率极高 …