We review recently developed reference methods based on mass fragmentography (specific
ion monitoring) with use of isotope-labeled internal standard, for determination of …

The value of mass spectrometry äs an analytical technique lies in its potential for structural
and quantitative measurement, eg it combines the specific detection of a selected compound …

A rapid gas chromatographic-mass spectrometric method for [15 N] urea analysis is
described which is based on the formation of a TFA-urea derivative. The method is …

A simple and rapid quantitative method for 13C-labelled urea ([13C] urea) in human serum
was developed by using high-performance liquid chromatography-atmospheric pressure …

Elevation in one or more compounds in exhaled breath condensate (EBC) has been
reported to be related to one or another lung disease. The increased concentration might be …

Abstract A GC-MS determination of urea in serum or spent dialysate is described, using 13 C
15 N 2-labelled urea and assaying the area ratio of labelled to natural urea by mass …

A compilation of selected references to the use of 15N in biochemical, pharmacological,
clinical and environmental applications for the period 1971–1976 is presented. Author and …

A selected ion-monitoring method, incorporating an internal standard, was developed to
allow the direct and simultaneous measurement of stable isotopelabelled urea and …

Mass spectrometry(MS) in its modem and advanced form has been rrsed for approximately
ten years in clinical and clinicahy related laboratories. However, it should not remain …

Chapter 13 Reference Methods Page 1 Chapter 13 Reference Methods L. Siekmann 1
Introduction 2 General Principles of Isotope Dilution-Mass Spectrometry (ID-MS) 2.1 …