Aging is a natural aspect of mammalian life. Although cellular mortality is inevitable, various
diseases can hasten the aging process, resulting in abnormal or premature senescence. As …

Ossification of the ligamentum flavum (OLF) is an uncommon but potentially serious spinal
condition which can cause progressive compression of the spinal canal with associated …

Background Ossification of ligamentum flavum (OLF) is an insidious and debilitating
heterotopic ossifying disease with etiological heterogeneity and undefined pathogenesis …

Spinal stenosis is a common degenerative spine disorder in the aged population and the
spinal ligament aging is a main contributor to this chronic disease. However, the underlying …

Background Hypertrophy of ligamentum flavum (HLF) is a common lumbar degeneration
disease (LDD) with typical symptoms of low back pain and limb numbness owing to an …

Background Thoracic ossification of ligamentum flavum (TOLF) can be asymptomatic and
progress insidiously. But, long-term follow-up results of clinical progression of TOLF are still …

Study Design Bioinformatics analysis of Gene Expression Omnibus (GEO). Background
Ossification of the ligamentum flavum (OLF) and ankylosing spondylitis (AS) represent …

Study Design Literature Review. Objective Myelopathy affecting the thoracic spinal cord can
arise secondary to several aetiologies which have similar presentation and management …

Purpose Genetic factors play a crucial role in thoracic ossification of the ligamentum flavum
(TOLF). This study aimed to better understand the association between single nucleotide …

Pathological changes in the ligamentum flavum (LF) can be defined as a process of chronic
progressive aberrations in the nature and structure of ligamentous tissues characterized by …