Epigenetic marking systems confer stability of gene expression during mammalian
development. Genome-wide epigenetic reprogramming occurs at stages when …

Epigenetic processes affect three stages of germline development, namely (1) specification
and formation of primordial germ cells and their germline derivatives through lineage …

The epigenomes of early mammalian embryos are extensively reprogrammed to acquire a
totipotent developmental potential. A major initial event in this reprogramming is the active …

We report on observations of the global methylation/demethylation pattern of both pronuclei
in human zygotes and in early embryos up to the blastocyst stage. Our results demonstrate …

Preimplantation embryo development involves four stages: fertilization, cell cleavage,
morula and blastocyst formation. During these stages, maternal and zygotic epigenetic …

Background In the mouse zygote the paternal genome undergoes dramatic structural and
epigenetic changes. Chromosomes are decondensed, protamines replaced by histones and …

There is species divergence in control of DNA methylation during preimplantation
development. The exact pattern of methylation in the bovine embryo has not been …

Epigenetics provides a means of understanding how environmental factors might alter
heritable changes in gene expression without changing DNA sequence, and hence the …

Preimplantation development directs the formation of an implantation-or attachment-
competent embryo so that metabolic interactions with the uterus can occur, pregnancy can …

DNA demethylation and remethylation are crucial for reprogramming of the differentiated
parental/somatic genome in the recipient ooplasm upon somatic cell nuclear transfer. Here …