Epigenetic reprogramming in mammals
HD Morgan, F Santos, K Green… - Human molecular …, 2005 - academic.oup.com
Epigenetic marking systems confer stability of gene expression during mammalian
development. Genome-wide epigenetic reprogramming occurs at stages when …
development. Genome-wide epigenetic reprogramming occurs at stages when …
[HTML][HTML] Epigenetics and the germline
Epigenetic processes affect three stages of germline development, namely (1) specification
and formation of primordial germ cells and their germline derivatives through lineage …
and formation of primordial germ cells and their germline derivatives through lineage …
[HTML][HTML] 5-Hydroxymethylcytosine in the mammalian zygote is linked with epigenetic reprogramming
M Wossidlo, T Nakamura, K Lepikhov… - Nature …, 2011 - nature.com
The epigenomes of early mammalian embryos are extensively reprogrammed to acquire a
totipotent developmental potential. A major initial event in this reprogramming is the active …
totipotent developmental potential. A major initial event in this reprogramming is the active …
[HTML][HTML] DNA methylation pattern in human zygotes and developing embryos
H Fulka, M Mrazek, O Tepla, J Fulka - Reproduction, 2004 - rep.bioscientifica.com
We report on observations of the global methylation/demethylation pattern of both pronuclei
in human zygotes and in early embryos up to the blastocyst stage. Our results demonstrate …
in human zygotes and in early embryos up to the blastocyst stage. Our results demonstrate …
[HTML][HTML] Epigenetic regulation in mammalian preimplantation embryo development
L Shi, J Wu - Reproductive Biology and Endocrinology, 2009 - Springer
Preimplantation embryo development involves four stages: fertilization, cell cleavage,
morula and blastocyst formation. During these stages, maternal and zygotic epigenetic …
morula and blastocyst formation. During these stages, maternal and zygotic epigenetic …
[HTML][HTML] Differential dynamics of histone H3 methylation at positions K4 and K9 in the mouse zygote
K Lepikhov, J Walter - BMC developmental biology, 2004 - Springer
Background In the mouse zygote the paternal genome undergoes dramatic structural and
epigenetic changes. Chromosomes are decondensed, protamines replaced by histones and …
epigenetic changes. Chromosomes are decondensed, protamines replaced by histones and …
[HTML][HTML] Dynamics of DNA methylation during early development of the preimplantation bovine embryo
There is species divergence in control of DNA methylation during preimplantation
development. The exact pattern of methylation in the bovine embryo has not been …
development. The exact pattern of methylation in the bovine embryo has not been …
Animal models to study environmental epigenetics
CS Rosenfeld - Biology of reproduction, 2010 - academic.oup.com
Epigenetics provides a means of understanding how environmental factors might alter
heritable changes in gene expression without changing DNA sequence, and hence the …
heritable changes in gene expression without changing DNA sequence, and hence the …
Preimplantation embryo programming: transcription, epigenetics, and culture environment.
V Duranthon, AJ Watson, P Lonergan - Reproduction (Cambridge …, 2008 - ir.lib.uwo.ca
Preimplantation development directs the formation of an implantation-or attachment-
competent embryo so that metabolic interactions with the uterus can occur, pregnancy can …
competent embryo so that metabolic interactions with the uterus can occur, pregnancy can …
DNA methylation in porcine preimplantation embryos developed in vivo and produced by in vitro fertilization, parthenogenetic activation and somatic cell nuclear …
DNA demethylation and remethylation are crucial for reprogramming of the differentiated
parental/somatic genome in the recipient ooplasm upon somatic cell nuclear transfer. Here …
parental/somatic genome in the recipient ooplasm upon somatic cell nuclear transfer. Here …