Mutations of isocitrate dehydrogenase 1 (IDH1) gene are most common in glioma, arguably
preceding all known genetic alterations during tumor development. IDH1 mutations nearly …

Background Glioblastoma multiforme (GBM) is the most common malignant and lethal type
of primary central nervous system tumor in humans. In spite of its high lethality, a small …

Despite the well-accepted notion that early maternal influences persist beyond fetal life and
may underlie many adult diseases, the risks imposed by the maternal environment on breast …

Data mining, a part of the Knowledge Discovery in Databases process (KDD), is the process
of extracting patterns from large data sets by combining methods from statistics and artificial …

This study was undertaken to examine the effect of cerium dioxide nanoparticles on the
expression levels of genes, encoded transcription and growth factors, which are important …

Summary Roundabout 1 (Robo1) is a transmembrane receptor of the immunoglobulin
family. Slit2 is one of its ligands. The function of Slit2/Robo1 signaling in the development of …

DNA methylation plays an important role in cancer biology and methylation events are
important prognostic and predictive markers in many tumor types. We have used methylation …

Background: The aim of this study was to elucidate the clinicopathological significance of
enhancer of zeste homolog 2 (EZH2) expression in gliomas, including its incidence and …

Background Glioblastoma multiforme (GBM) is a heterogeneous CNS neoplasm which
causes significant morbidity and mortality. One reason for the poor prognostic outcome of …

Cancer cells and embryonic stem (ES) cells share several biological properties, suggesting
that some genes expressed in ES cells may play an important role in cancer cell growth. In …