Understanding the evolutionary and ecological roles of'non-genetic'inheritance (NGI) is
daunting due to the complexity and diversity of epigenetic mechanisms. We draw on insights …

Cytosine DNA methylation (5mC) is a widespread base modification in eukaryotic genomes
with critical roles in transcriptional regulation. In recent years, our understanding of 5mC has …

Epigenetic pathways are essential in different biological processes and in phenotype-
environment interactions in response to different stressors and they can induce phenotypic …

Human evolution has shaped gender differences between males and females. Over the
years, scientific studies have proposed that epigenetic modifications significantly influence …

The origin story and emergence of molecular biology is muddled. The early triumphs in
bacterial genetics and the complexity of animal and plant genomes complicate an intricate …

The evolutionary significance of epigenetic inheritance is controversial. While epigenetic
marks such as DNA methylation can affect gene function and change in response to …

A wide range of chemicals have been identified as endocrine disrupting chemicals (EDCs)
in vertebrate species. Most studies of EDCs have focused on exposure of both male and …

The inland silverside, Menidia beryllina, is a euryhaline fish and a model organism in
ecotoxicology. We previously showed that exposure to picomolar (ng/L) levels of endocrine …

Abstract Changes in DNA methylation at specific CpG sites have been used to build
predictive models to estimate animal age, predominantly in mammals. Little testing for this …

Spatiotemporal regulation of cell type-specific gene expression is essential to convert a
zygote into a complex organism that contains hundreds of distinct cell types. A class of cis …