Chronic activation of the renin‐angiotensin‐aldosterone system (RAAS) promotes and
perpetuates the syndromes of congestive heart failure, systemic hypertension, and chronic …

Glucocorticoid hormones (cortisol and corticosterone-CORT) are the effector hormones of
the hypothalamic-pituitary-adrenal (HPA) axis neuroendocrine system. CORT is a systemic …

Steroidogenesis, the processes by which cholesterol is converted to steroid hormones,
involves transport proteins, enzymes, redox partners and cofactors. Most steroidogenic …

Glucocorticoid action on target tissues is determined by the density of “nuclear” receptors
and intracellular metabolism by the two isozymes of 11β-hydroxysteroid dehydrogenase …

Traditional and scientific evidence attribute numerous bioactivities of Licorice (Glycyrrhiza
glabra Linn.) in aging-related disorders. In this state-of-art review, an extensive search in …

Thirst motivates animals to find and consume water. More than 40 years ago, a set of
interconnected brain structures known as the lamina terminalis was shown to govern thirst …

The primary adrenal cortical steroid hormones, aldosterone, and the glucocorticoids cortisol
and corticosterone, act through the structurally similar mineralocorticoid (MR) and …

Brain Corticosteroid Receptor Balance in Health and Disease* | Endocrine Reviews | Oxford
Academic Skip to Main Content Advertisement Oxford Academic Journals Books Search Menu …

Introduction T HE hippocampus has received considerable attention as a potential regulator
of the hypothalamic-pituitary-adrenocortical (HPA) axis. After the demonstration by Harris' …

The steroid hormone aldosterone regulates sodium and potassium homeostasis.
Aldosterone and activation of the mineralocorticoid receptor also causes inflammation and …