The tumor microenvironment affects the structure and metabolic function of mitochondria in
tumor cells. This process involves changes in metabolic activity, an increase in the amount …

Cisplatin is a first-line chemotherapeutic agent in the treatment of malignant tumors with
remarkable clinical effects and low cost. However, the ototoxicity and neurotoxicity of …

Hydrogen sulfide (H 2 S) is the most recently discovered gasotransmitter molecule that
activates multiple intracellular signaling pathways and exerts concentration-dependent …

Combined chemotherapy and targeted therapy holds immense potential in the management
of advanced gastric cancer (GC). GC tissues exhibit an elevated expression level of protein …

Nerve damage caused by accumulated oxidative stress is one of the characteristics and
main mechanisms of Alzheimer's disease (AD). Previous studies have shown that …

Multidrug combination therapy in the inner ear faces diverse challenges due to the distinct
physicochemical properties of drugs and the difficulties of overcoming the oto‐biologic …

There are significant challenges in developing drug carriers for therapeutic perspective. We
have investigated a novel nanocarrier system, based on combining functionalized magnetic …

The effectiveness of chemotherapeutic agents for hepatocellular carcinoma (HCC) is
unsatisfactory because of tumor heterogeneity, multidrug resistance, and poor target …

Lysophosphatidic acid (LPA) is an active phospholipid signaling molecule that binds to six
specific G protein-coupled receptors (LPA1-6) on the cell surface and exerts a variety of …

Self-healing coatings have shown promise in controlling the degradation of scaffolds and
addressing coating detachment issues. However, developing a self-healing coating for …