Extracellular matrix, via its receptors the integrins, has emerged as a crucial factor in cancer
development. The α2β1 integrin is a major collagen receptor that is widely expressed and …

The integrin “very late antigen-4”(VLA-4) is expressed by numerous cells of hematopoietic
origin and possesses a key function in the cellular immune response, eg, by mediating …

Purpose Although CD49d is an unfavorable prognostic marker in chronic lymphocytic
leukemia (CLL), definitive validation evidence is lacking. A worldwide multicenter analysis …

¡ Ya está! Después de estos años en el laboratorio llego a la meta y puedo dar las gracias a
las personas que me han acompañado en este camino. Espero no dejarme a nadie en el …

Interaction of chronic lymphocytic leukemia (CLL) B cells with tissue microenvironment has
been suggested to favor disease progression by promoting malignant B-cell growth …

CD49d and CD38 are independent negative prognostic markers in chronic lymphocytic
leukemia (CLL). Their associated expression marks a disease subset with a highly …

Chronic lymphocytic leukemia (CLL) is an indolent lymphoproliferative disorder
characterized by both circulating peripheral disease as well as involvement of the lymph …

The interactions of chronic lymphocytic leukemia cells with the microenvironment in
secondary lymphoid tissues and the bone marrow are known to promote CLL cell survival …

Chronic lymphocytic leukemia (CLL) is a heterogeneous disease with a variable clinical
course. Novel biomarkers discovered over the past 20 years have revolutionized the way …

Flow Cytometry of Hematological Malignancies Flow cytometric analysis is often integral to
the swift and accurate diagnosis of leukemias and lymphomas of the blood, bone marrow …