Tracking of extracellular vesicles' biodistribution: new methods and approaches

AM Aimaletdinov, MO Gomzikova - International Journal of Molecular …, 2022 - mdpi.com
Extracellular vesicles (EVs) are nanosized lipid bilayer vesicles that are released by almost
all cell types. They range in diameter from 30 nm to several micrometres and have the ability …

Emerging extracellular vesicle-based carriers for glioblastoma diagnosis and therapy

J Wang, Y Liu, F Liu, S Gan, S Roy, I Hasan, B Zhang… - Nanoscale, 2023 - pubs.rsc.org
Glioblastoma (GBM) treatment is still a big clinical challenge because of its highly malignant,
invasive, and lethal characteristics. After treatment with the conventional therapeutic …

microRNAs‐based diagnostic and therapeutic applications in liver fibrosis

X Zhao, X Xue, Z Cui, F Kwame Amevor… - Wiley …, 2023 - Wiley Online Library
Liver fibrosis is a process of over‐extracellular matrix (ECM) aggregation and angiogenesis,
which develops into cirrhosis and hepatocellular carcinoma (HCC). With the increasing …

Engineered extracellular vesicle-encapsulated CHIP as novel nanotherapeutics for treatment of renal fibrosis

C Ji, J Zhang, L Shi, H Shi, W Xu, J Jin… - NPJ Regenerative …, 2024 - nature.com
Renal interstitial fibrosis (RIF) is a fundamental pathological feature of chronic kidney
disease (CKD). However, toxicity and poor renal enrichment of fibrosis inhibitors limit their …

Extracellular vesicles as new players in drug delivery: a focus on red blood cells-derived EVs

S Biagiotti, F Abbas, M Montanari, C Barattini, L Rossi… - Pharmaceutics, 2023 - mdpi.com
The article is divided into several sections, focusing on extracellular vesicles'(EVs) nature,
features, commonly employed methodologies and strategies for their isolation/preparation …

Improving the circulation time and renal therapeutic potency of extracellular vesicles using an endogenous ligand binding strategy

S Liu, K Lv, Y Wang, P Lou, P Zhou, C Wang… - Journal of Controlled …, 2022 - Elsevier
Kidney diseases are a serious health issue worldwide, and novel therapeutics are urgently
needed. Extracellular vesicles (EVs) have emerged as potent drug delivery systems (DDSs) …

A quantitative review of nanotechnology‐based therapeutics for kidney diseases

HT Cheng, YN Ngoc Ta, T Hsia… - Wiley Interdisciplinary …, 2024 - Wiley Online Library
Kidney‐specific nanocarriers offer a targeted approach to enhance therapeutic efficacy and
reduce off‐target effects in renal treatments. The nanocarriers can achieve organ or cell …

[HTML][HTML] An update on renal fibrosis: from mechanisms to therapeutic strategies with a focus on extracellular vesicles

C Wang, SW Li, X Zhong, BC Liu… - Kidney Research and …, 2023 - ncbi.nlm.nih.gov
The increasing prevalence of chronic kidney disease (CKD) is a major global public health
concern. Despite the complicated pathogenesis of CKD, renal fibrosis represents the most …

Application of nanotechnology in the treatment of glomerulonephritis: current status and future perspectives

HQ Zhan, X Zhang, XL Chen, L Cheng… - Journal of …, 2024 - Springer
Glomerulonephritis (GN) is the most common cause of end-stage renal failure worldwide; in
most cases, it cannot be cured and can only delay the progression of the disease. At …

[HTML][HTML] Extracellular vesicle biopotentiated hydrogels for diabetic wound healing: The art of living nanomaterials combined with soft scaffolds

Z Yan, T Zhang, Y Wang, S Xiao, J Gao - Materials Today Bio, 2023 - Elsevier
Diabetic wounds (DWs) pose a major challenge for the public health system owing to their
high incidence, complex pathogenesis, and long recovery time; thus, there is an urgent need …