Genetic architecture of childhood speech disorder: a review

AT Morgan, DJ Amor, MD St John, IE Scheffer… - Molecular …, 2024 - nature.com
Severe speech disorders lead to poor literacy, reduced academic attainment and negative
psychosocial outcomes. As early as the 1950s, the familial nature of speech disorders was …

[HTML][HTML] Prenatal exposure to phthalates and peripheral blood and buccal epithelial DNA methylation in infants: an epigenome-wide association study

G England-Mason, SM Merrill, N Gladish… - Environment …, 2022 - Elsevier
Background Prenatal exposure to phthalates has been associated with adverse health and
neurodevelopmental outcomes. DNA methylation (DNAm) alterations may be a mechanism …

Integrated multi-omics reveal epigenomic disturbance of assisted reproductive technologies in human offspring

W Chen, Y Peng, X Ma, S Kong, S Tan, Y Wei… - …, 2020 - thelancet.com
Background The births of more than 8 million infants have been enabled globally through
assisted reproductive technologies (ARTs), including conventional in vitro fertilization (IVF) …

Expanding the phenome and variome of skeletal dysplasia

S Maddirevula, S Alsahli, L Alhabeeb, N Patel… - Genetics in …, 2018 - nature.com
Expanding the phenome and variome of skeletal dysplasia | Genetics in Medicine Skip to main
content Thank you for visiting nature.com. You are using a browser version with limited support …

Cancer-derived exosomal miR-375 targets DIP2C and promotes osteoblastic metastasis and prostate cancer progression by regulating the Wnt signaling pathway

Y Liu, C Yang, S Chen, W Liu, J Liang, S He… - Cancer Gene …, 2023 - nature.com
Bone metastasis is the most common complication responsible for most deaths in the
advanced stages of prostate cancer (PCa). However, the exact mechanism of bone …

DNA methylation in babies born to nonsmoking mothers exposed to secondhand smoke during pregnancy: an epigenome-wide association study

BF Fuemmeler, MG Dozmorov, EK Do… - Environmental …, 2021 - ehp.niehs.nih.gov
Background: Maternal smoking during pregnancy is related to altered DNA methylation in
infant umbilical cord blood. The extent to which low levels of smoke exposure among …

Multi-CpG linear regression models to accurately predict paclitaxel and docetaxel activity in cancer cell lines

MD Bacolod, PB Fisher, F Barany - Advances in Cancer Research, 2023 - Elsevier
The microtubule-targeting paclitaxel (PTX) and docetaxel (DTX) are widely used
chemotherapeutic agents. However, the dysregulation of apoptotic processes, microtubule …

Macrophage maturation from blood monocytes is altered in people with HIV, and is linked to serum lipid profiles and activation indices: a model for studying …

ER Bowman, CM Cameron, B Richardson… - PLoS …, 2020 - journals.plos.org
People with HIV (PWH) are at increased risk for atherosclerotic cardiovascular disease
(ASCVD). Proportions of vascular homing monocytes are enriched in PWH; however, little is …

Chicken Hypothalamic and Ovarian DNA Methylome Alteration in Response to Forced Molting

T Zhang, C Li, J Deng, Y Jia, L Qu, Z Ning - Animals, 2023 - mdpi.com
Simple Summary Forced molting refers to the systemic stress response of laying hens
caused by some externally imposed artificial measures (such as starvation), resulting in …

DNA methylome in visceral adipose tissue can discriminate patients with and without colorectal cancer

AG Izquierdo, H Boughanem, A Diaz-Lagares… - Epigenetics, 2022 - Taylor & Francis
Adipose tissue dysfunction, particularly the visceral (VAT) compartment, has been proposed
to play a relevant role in colorectal cancer (CRC) development and progression. Epigenetic …