Abstract Purpose of Review Obesity is a chronic disease, a major public health problem due
to its association with non-communicable diseases and all-cause mortality. Indeed, people …

Growing evidence supports the hypothesis that dietary factors may play a role in systemic
low-grade chronic inflammation. Summary evidence from randomized controlled trials has …

Morbidity and mortality of cardiovascular diseases (CVDs) are exceedingly high worldwide.
Researchers have found that the occurrence and development of CVDs are closely related …

In this comprehensive review, we examine the main preclinical and clinical investigations
assessing the effects of different forms of choline supplementation currently available …

Accumulating evidence suggested that both gut microbiome and sex play a critical role in
the efficacy of immune checkpoint blockade therapy. Considering the reciprocal relationship …

Background Fasting is beneficial in many diseases, including rheumatoid arthritis (RA), with
lasting effects for up to 1 year. However, existing data dates back several decades before …

Abstract Background In 1957, Francis Crick drew a linear diagram on a blackboard. This
diagram is often called the “central dogma.” Subsequently, the relationships between …

While it is well known from numerous epidemiologic investigations that social determinants
(socioeconomic, environmental, and psychosocial factors exposed to over the life-course) …

There is a clear correlation between gut microbiota, diet, and metabolic outcomes. A diet
high in fiber has been shown to decrease inflammation, increase insulin sensitivity, and …

Gut microbiota, a group of microorganisms that live in the gastrointestinal tract, plays
important roles in health and disease. One mechanism that gut microbiota in modulation of …