The pineal gland-derived indoleamine hormone, melatonin, regulates multiple cellular
processes, ranging from chronobiology, proliferation, apoptosis, and oxidative damage to …

Cancer cells selectively take up exogenous serine or synthesize serine via the serine
synthesis pathway for conversion into intracellular glycine and one‐carbon units for …

Background Long non-coding RNAs (lncRNAs) exert various functions in human cancers.
However, the biological functions of lncRNAs in non-small cell lung cancer (NSCLC) are …

Significant enhancement of the glycolysis pathway is a major feature of tumor cells, even in
the presence of abundant oxygen; this enhancement is known as the Warburg effect, and …

Background: Routine changes in cell metabolism can drive tumor development, as the
cellular program develops to promote glycolysis and redox homeostasis during tumor …

Cancer cells are characterized by accelerated proliferation and an outstanding adaptation of
their metabolic pathways to meet energy demands. The folate cycle, also known as folate …

MYCN amplification is an independent poor prognostic factor in patients with high-risk
neuroblastoma (NB). Further exploring the molecular regulatory mechanisms in MYCN …

The crosstalk between lung cancer cells and cancer-associated fibroblast (CAF) is pivotal in
cancer progression. Heat shock protein family D member 1 (HSPD1) is a potential …

Purpose Breast cancer is more likely attributed to a combination of genetic variations and
lifestyle factors. Both one-carbon metabolism and diet-related factors could interfere with the …

One-carbon metabolism plays a crucial role in tumorigenesis as it supplies the one-carbon
units necessary for nucleotide synthesis, epigenetic regulation, and redox metabolism …