DNA methyltransferases and epigenetic regulation in bacteria
S Adhikari, PD Curtis - FEMS microbiology reviews, 2016 - academic.oup.com
Epigenetics is a change in gene expression that is heritable without a change in DNA
sequence itself. This phenomenon is well studied in eukaryotes, particularly in humans for …
sequence itself. This phenomenon is well studied in eukaryotes, particularly in humans for …
Biosynthesis and function of modified bases in bacteria and their viruses
P Weigele, EA Raleigh - Chemical reviews, 2016 - ACS Publications
Naturally occurring modification of the canonical A, G, C, and T bases can be found in the
DNA of cellular organisms and viruses from all domains of life. Bacterial viruses …
DNA of cellular organisms and viruses from all domains of life. Bacterial viruses …
Mapping DNA methylation with high-throughput nanopore sequencing
DNA chemical modifications regulate genomic function. We present a framework for
mapping cytosine and adenosine methylation with the Oxford Nanopore Technologies …
mapping cytosine and adenosine methylation with the Oxford Nanopore Technologies …
An adenine base editor variant expands context compatibility
Adenine base editors (ABEs) are precise gene-editing agents that convert A: T pairs into G:
C through a deoxyinosine intermediate. Existing ABEs function most effectively when the …
C through a deoxyinosine intermediate. Existing ABEs function most effectively when the …
DNA phosphorothioate modification—a new multi-functional epigenetic system in bacteria
L Wang, S Jiang, Z Deng, PC Dedon… - FEMS microbiology …, 2019 - academic.oup.com
Synthetic phosphorothioate (PT) internucleotide linkages, in which a nonbridging oxygen is
replaced by a sulphur atom, share similar physical and chemical properties with …
replaced by a sulphur atom, share similar physical and chemical properties with …
The roles of nucleoid-associated proteins and topoisomerases in chromosome structure, strand segregation, and the generation of phenotypic heterogeneity in …
V Norris, C Kayser, G Muskhelishvili… - FEMS Microbiology …, 2023 - academic.oup.com
How to adapt to a changing environment is a fundamental, recurrent problem confronting
cells. One solution is for cells to organize their constituents into a limited number of spatially …
cells. One solution is for cells to organize their constituents into a limited number of spatially …
What water professionals should know about antibiotics and antibiotic resistance: an overview
In light of recent predictions that by 2050, antimicrobial resistance will cause almost 10
million deaths annually, costing the global economy 100 trillion US dollars, the examination …
million deaths annually, costing the global economy 100 trillion US dollars, the examination …
N6-methyladenine: a conserved and dynamic DNA mark
ZK O'Brown, EL Greer - DNA methyltransferases-role and function, 2016 - Springer
Chromatin, consisting of deoxyribonucleic acid (DNA) wrapped around histone proteins,
facilitates DNA compaction and allows identical DNA codes to confer many different cellular …
facilitates DNA compaction and allows identical DNA codes to confer many different cellular …
Genetic and metabolic engineering challenges of C1-gas fermenting acetogenic chassis organisms
Unabated mining and utilisation of petroleum and petroleum resources and their conversion
to essential fuels and chemicals have drastic environmental consequences, contributing to …
to essential fuels and chemicals have drastic environmental consequences, contributing to …
Epigenetic Switch Driven by DNA Inversions Dictates Phase Variation in Streptococcus pneumoniae
DNA methylation is an important epigenetic mechanism for phenotypic diversification in all
forms of life. We previously described remarkable cell-to-cell heterogeneity in epigenetic …
forms of life. We previously described remarkable cell-to-cell heterogeneity in epigenetic …