Simple and complex carbohydrates (glycans) have long been known to play major
metabolic, structural and physical roles in biological systems. Targeted microbial binding to …

Voltage-gated calcium channels are the primary mediators of depolarization-induced
calcium entry into neurons. There is great diversity of calcium channel subtypes due to …

BACKGROUND: Findings from family and twin studies suggest that genetic contributions to
psychiatric disorders do not in all cases map to present diagnostic categories. We aimed to …

Abstract The Taiwan Biobank (TWB) aims to build a nationwide research database that
integrates genomic/epigenomic profiles, lifestyle patterns, dietary habits, environmental …

This review summarises genetic studies in which calcium channel genes have been
connected to the spectrum of neuropsychiatric syndromes, from bipolar disorder and …

GABAB receptors (GABABRs) are G protein-coupled receptors for GABA, the main inhibitory
neurotransmitter in the CNS. In the past 5 years, notable advances have been made in our …

A large portion of common variant loci associated with genetic risk for schizophrenia reside
within noncoding sequence of unknown function. Here, we demonstrate promoter and …

Genome-wide association studies (GWASs) have identified several susceptibility loci for
bipolar disorder (BD) and shown that the genetic architecture of BD can be explained by …

Genome-wide expression analysis using next generation sequencing (RNA-Seq) provides
an opportunity for in-depth molecular profiling of fundamental biological processes, such as …

Meta-analyses of bipolar disorder (BD) genome-wide association studies (GWAS) have
identified several genome-wide significant signals in European-ancestry samples, but so far …