Recent developments in clinical plasma proteomics—applied to cardiovascular research

NB Palstrøm, R Matthiesen, LM Rasmussen, HC Beck - Biomedicines, 2022 - mdpi.com
The human plasma proteome mirrors the physiological state of the cardiovascular system, a
fact that has been used to analyze plasma biomarkers in routine analysis for the diagnosis …

[HTML][HTML] The role of immune mechanisms in abdominal aortic aneurysm: could it be a promising therapeutic strategy?

R Dinc - Acta Cardiologica Sinica, 2023 - ncbi.nlm.nih.gov
Abdominal aortic aneurysm (AAA) is an enlargement of the aorta greater than 50% in
diameter. Although up to 80% of cases result in mortality if the aneurysm ruptures, patients …

Neutrophil extracellular traps induce abdominal aortic aneurysm formation by promoting the synthetic and proinflammatory smooth muscle cell phenotype via Hippo …

S Yang, L Chen, Z Wang, J Chen, Q Ni, X Guo… - Translational …, 2023 - Elsevier
The neutrophil plays an important role during abdominal aortic aneurysm (AAA) formation by
undergoing histone citrullination with peptidyl arginine deiminase 4 (encoded by Padi4) and …

Causal role for neutrophil elastase in thoracic aortic dissection in mice

M Yang, X Zhou, SWA Pearce, Z Yang… - … and Vascular Biology, 2023 - Am Heart Assoc
BACKGROUND: Thoracic aortic dissection (TAD) is a life-threatening aortic disease without
effective medical treatment. Increasing evidence has suggested a role for NE (neutrophil …

Extracellular matrix remodeling biomarkers in coronary artery disease

P Theofilis, M Sagris, E Oikonomou… - Current Topics in …, 2022 - ingentaconnect.com
Atherosclerosis and one of its most serious consequences, coronary artery disease, are
important sources of morbidity and mortality globally, necessitating early detection and …

[HTML][HTML] Current state-of-the-art and utilities of machine learning for detection, monitoring, growth prediction, rupture risk assessment, and post-surgical management …

S Baek, A Arzani - Applications in Engineering Science, 2022 - Elsevier
Ultrasound imaging has long been playing a central role in detecting abdominal aortic
aneurysms (AAAs). With a recent trend of reducing prevalence of AAAs, ultrasound …

Relationship between the levels of calprotectin and soluble receptor for advanced glycation end products with abdominal aortic aneurysm diameter: A preliminary …

W Hauzer, J Gnus, J Rosińczuk - Journal of Clinical Medicine, 2022 - mdpi.com
An abdominal aortic aneurysm (AAA) is a dilatation of the abdominal aorta greater than 50%
of the diameter of a healthy aorta. Previous experimental studies confirm the effect of …

脂代谢对主动脉疾病发生发展及预后的影响

王宇航, 沈振亚 - 中华全科医学, 2023 - zhqkyx.net
以主动脉瘤和主动脉夹层为代表的主动脉疾病作为一类高发病率和高死亡率的疾病受到广泛
重视, 其缺乏有效的早期预警标志, 同时, 手术治疗死亡率也较高. 主动脉疾病的发病机制尚未 …

Prediction of abdominal aortic aneurysm growth by artificial intelligence taking into account clinical, biologic, morphologic, and biomechanical variables

N Kontopodis, M Klontzas, K Tzirakis… - …, 2023 - journals.sagepub.com
Objectives To develop a prediction model that could risk stratify abdominal aortic aneurysms
(AAAs) into high and low growth rate groups, using machine learning algorithms based on …

Biomarkers in EndoVascular Aneurysm Repair (EVAR) and abdominal aortic aneurysm: pathophysiology and clinical implications

F Stilo, V Catanese, A Nenna, N Montelione… - Diagnostics, 2022 - mdpi.com
Circulating biomarkers have been recently investigated among patients undergoing
endovascular aortic aneurysm repair (EVAR) for abdominal aortic aneurysm (AAA) …