[HTML][HTML] Mammalian transient receptor potential TRPA1 channels: from structure to disease
K Talavera, JB Startek, J Alvarez-Collazo… - Physiological …, 2020 - journals.physiology.org
The transient receptor potential ankyrin (TRPA) channels are Ca 2+-permeable nonselective
cation channels remarkably conserved through the animal kingdom. Mammals have only …
cation channels remarkably conserved through the animal kingdom. Mammals have only …
Transient receptor potential (TRP) channels
A Samanta, TET Hughes… - … complexes: Structure and …, 2018 - Springer
Abstract Transient Receptor Potential (TRP) channels are evolutionarily conserved integral
membrane proteins. The mammalian TRP superfamily of ion channels consists of 28 cation …
membrane proteins. The mammalian TRP superfamily of ion channels consists of 28 cation …
Structure of the TRPA1 ion channel suggests regulatory mechanisms
The TRPA1 ion channel (also known as the wasabi receptor) is a detector of noxious
chemical agents encountered in our environment or produced endogenously during tissue …
chemical agents encountered in our environment or produced endogenously during tissue …
TRPA1 as a therapeutic target for nociceptive pain
D Souza Monteiro de Araujo, R Nassini… - Expert opinion on …, 2020 - Taylor & Francis
Introduction Chronic pain affects approximatively 30–50% of the population globally.
Pathologies such as migraine, diabetic neuropathy, nerve injury and treatment with …
Pathologies such as migraine, diabetic neuropathy, nerve injury and treatment with …
[HTML][HTML] Molecular mechanism of TRP channels
J Zheng - Comprehensive Physiology, 2013 - ncbi.nlm.nih.gov
Transient receptor potential (TRP) channels are cellular sensors for a wide spectrum of
physical and chemical stimuli. They are involved in the formation of sight, hearing, touch …
physical and chemical stimuli. They are involved in the formation of sight, hearing, touch …
TRPA1: A gatekeeper for inflammation
DM Bautista, M Pellegrino… - Annual review of …, 2013 - annualreviews.org
Tissue damage evokes an inflammatory response that promotes the removal of harmful
stimuli, tissue repair, and protective behaviors to prevent further damage and encourage …
stimuli, tissue repair, and protective behaviors to prevent further damage and encourage …
Membrane protein structural biology in the era of single particle cryo-EM
Y Cheng - Current opinion in structural biology, 2018 - Elsevier
In the past few years, significant technological breakthroughs in single particle cryo-electron
microscopy enabled a 'resolution revolution'of this technique. It also changed structural …
microscopy enabled a 'resolution revolution'of this technique. It also changed structural …
The transient receptor potential channel TRPA1: from gene to pathophysiology
B Nilius, G Appendino, G Owsianik - Pflügers Archiv-European Journal of …, 2012 - Springer
Abstract The Transient Receptor Potential Ankyrin 1 channel (TRPA1), is a member of the
large TRP family of ion channels, and functions as a Ca 2+ permeable non-selective cation …
large TRP family of ion channels, and functions as a Ca 2+ permeable non-selective cation …
[HTML][HTML] The regulatory and modulatory roles of TRP family channels in malignant tumors and relevant therapeutic strategies
T Zhong, W Zhang, H Guo, X Pan, X Chen, Q He… - … Pharmaceutica Sinica B, 2022 - Elsevier
Transient receptor potential (TRP) channels are one primary type of calcium (Ca 2+)
permeable channels, and those relevant transmembrane and intracellular TRP channels …
permeable channels, and those relevant transmembrane and intracellular TRP channels …
Trpa1
PM Zygmunt, ED Högestätt - … potential (TRP) cation channels: volume I, 2014 - Springer
The transient receptor potential ankyrin subtype 1 protein (TRPA1) is a nonselective cation
channel permeable to Ca 2+, Na+, and K+. TRPA1 is a promiscuous chemical nocisensor …
channel permeable to Ca 2+, Na+, and K+. TRPA1 is a promiscuous chemical nocisensor …