Biologics for treatment of atopic dermatitis: current status and future prospect
T Ratchataswan, TM Banzon, JP Thyssen… - The Journal of Allergy …, 2021 - Elsevier
Atopic dermatitis (AD) is a common inflammatory skin disease characterized by intense
pruritus and recurrent eczematous lesions that significantly impair quality of life. It is a …
pruritus and recurrent eczematous lesions that significantly impair quality of life. It is a …
[HTML][HTML] Recent advances in understanding the role of IL-4 signaling
Abstract Interleukin-4 (IL-4) is a four-α-helical bundle type I cytokine with broad pleiotropic
actions on multiple lineages. Major actions of IL-4 were initially discovered for B and T cells …
actions on multiple lineages. Major actions of IL-4 were initially discovered for B and T cells …
[HTML][HTML] Multifaceted analysis of cross-tissue transcriptomes reveals phenotype–endotype associations in atopic dermatitis
A Sekita, H Kawasaki, A Fukushima-Nomura… - Nature …, 2023 - nature.com
Atopic dermatitis (AD) is a skin disease that is heterogeneous both in terms of clinical
manifestations and molecular profiles. It is increasingly recognized that AD is a systemic …
manifestations and molecular profiles. It is increasingly recognized that AD is a systemic …
[HTML][HTML] Effective management of severe asthma with biologic medications in adult patients: a literature review and international expert opinion
Severe asthma often remains uncontrolled despite effective treatments and evidence-based
guidelines. A group of global experts in asthma and biologic medications from 9 countries …
guidelines. A group of global experts in asthma and biologic medications from 9 countries …
[HTML][HTML] Effect of neferine on DNCB-induced atopic dermatitis in HaCaT cells and BALB/c mice
CC Yang, YL Hung, WC Ko, YJ Tsai, JF Chang… - International journal of …, 2021 - mdpi.com
Atopic dermatitis (AD) is a chronic and persistent inflammatory skin disease characterized by
eczematous lesions and itching, and it has become a serious health problem. However, the …
eczematous lesions and itching, and it has become a serious health problem. However, the …
Efficacy and safety of Janus kinase inhibitors for the treatment of atopic dermatitis: a systematic review and meta-analysis
C Li, X Sun, K Zhao, F Meng, L Li, Z Mu, X Han - Dermatology, 2022 - karger.com
Background: Current therapeutic options for atopic dermatitis (AD) are limited. Janus kinase
(JAK) inhibitors may be viable alternatives. Objectives: To assess the efficacy and safety of …
(JAK) inhibitors may be viable alternatives. Objectives: To assess the efficacy and safety of …
[HTML][HTML] Atopic dermatitis as a multifactorial skin disorder. Can the analysis of pathophysiological targets represent the winning therapeutic strategy?
I Magnifico, G Petronio Petronio, N Venditti, MA Cutuli… - Pharmaceuticals, 2020 - mdpi.com
Atopic dermatitis (AD) is a pathological skin condition with complex aetiological mechanisms
that are difficult to fully understand. Scientific evidence suggests that of all the causes, the …
that are difficult to fully understand. Scientific evidence suggests that of all the causes, the …
[HTML][HTML] Cannabinoid Compounds as a pharmacotherapeutic option for the treatment of non-cancer skin diseases
R Ramer, B Hinz - Cells, 2022 - mdpi.com
The endocannabinoid system has been shown to be involved in various skin functions, such
as melanogenesis and the maintenance of redox balance in skin cells exposed to UV …
as melanogenesis and the maintenance of redox balance in skin cells exposed to UV …
The efficacy of Lactocare® synbiotic on the clinical symptoms in patients with psoriasis: a randomized, double‐blind, placebo‐controlled clinical trial
A Akbarzadeh, P Alirezaei… - Dermatology …, 2022 - Wiley Online Library
Background. Attention to the administration of probiotics for the treatment of psoriasis has
recently increased. Aim. In the present study, improvements in dermatology life quality index …
recently increased. Aim. In the present study, improvements in dermatology life quality index …
Morus alba fruits attenuates atopic dermatitis symptoms and pathology in vivo and in vitro via the regulation of barrier function, immune response and pruritus
Background Morus alba fruits (MAF) belong to the Moraceae family, which are known to be
effective in treating diabetic, autoimmune, and hormonal diseases owing to its low toxicity …
effective in treating diabetic, autoimmune, and hormonal diseases owing to its low toxicity …