Biologics for treatment of atopic dermatitis: current status and future prospect

T Ratchataswan, TM Banzon, JP Thyssen… - The Journal of Allergy …, 2021 - Elsevier
Atopic dermatitis (AD) is a common inflammatory skin disease characterized by intense
pruritus and recurrent eczematous lesions that significantly impair quality of life. It is a …

[HTML][HTML] Recent advances in understanding the role of IL-4 signaling

AD Keegan, WJ Leonard, J Zhu - Faculty reviews, 2021 - ncbi.nlm.nih.gov
Abstract Interleukin-4 (IL-4) is a four-α-helical bundle type I cytokine with broad pleiotropic
actions on multiple lineages. Major actions of IL-4 were initially discovered for B and T cells …

[HTML][HTML] Multifaceted analysis of cross-tissue transcriptomes reveals phenotype–endotype associations in atopic dermatitis

A Sekita, H Kawasaki, A Fukushima-Nomura… - Nature …, 2023 - nature.com
Atopic dermatitis (AD) is a skin disease that is heterogeneous both in terms of clinical
manifestations and molecular profiles. It is increasingly recognized that AD is a systemic …

[HTML][HTML] Effective management of severe asthma with biologic medications in adult patients: a literature review and international expert opinion

R Buhl, E Bel, A Bourdin, I Dávila, JA Douglass… - The Journal of Allergy …, 2022 - Elsevier
Severe asthma often remains uncontrolled despite effective treatments and evidence-based
guidelines. A group of global experts in asthma and biologic medications from 9 countries …

[HTML][HTML] Effect of neferine on DNCB-induced atopic dermatitis in HaCaT cells and BALB/c mice

CC Yang, YL Hung, WC Ko, YJ Tsai, JF Chang… - International journal of …, 2021 - mdpi.com
Atopic dermatitis (AD) is a chronic and persistent inflammatory skin disease characterized by
eczematous lesions and itching, and it has become a serious health problem. However, the …

Efficacy and safety of Janus kinase inhibitors for the treatment of atopic dermatitis: a systematic review and meta-analysis

C Li, X Sun, K Zhao, F Meng, L Li, Z Mu, X Han - Dermatology, 2022 - karger.com
Background: Current therapeutic options for atopic dermatitis (AD) are limited. Janus kinase
(JAK) inhibitors may be viable alternatives. Objectives: To assess the efficacy and safety of …

[HTML][HTML] Atopic dermatitis as a multifactorial skin disorder. Can the analysis of pathophysiological targets represent the winning therapeutic strategy?

I Magnifico, G Petronio Petronio, N Venditti, MA Cutuli… - Pharmaceuticals, 2020 - mdpi.com
Atopic dermatitis (AD) is a pathological skin condition with complex aetiological mechanisms
that are difficult to fully understand. Scientific evidence suggests that of all the causes, the …

[HTML][HTML] Cannabinoid Compounds as a pharmacotherapeutic option for the treatment of non-cancer skin diseases

R Ramer, B Hinz - Cells, 2022 - mdpi.com
The endocannabinoid system has been shown to be involved in various skin functions, such
as melanogenesis and the maintenance of redox balance in skin cells exposed to UV …

The efficacy of Lactocare® synbiotic on the clinical symptoms in patients with psoriasis: a randomized, double‐blind, placebo‐controlled clinical trial

A Akbarzadeh, P Alirezaei… - Dermatology …, 2022 - Wiley Online Library
Background. Attention to the administration of probiotics for the treatment of psoriasis has
recently increased. Aim. In the present study, improvements in dermatology life quality index …

Morus alba fruits attenuates atopic dermatitis symptoms and pathology in vivo and in vitro via the regulation of barrier function, immune response and pruritus

HM Kim, YM Kang, BR Jin, H Lee, DS Lee, M Lee… - Phytomedicine, 2023 - Elsevier
Background Morus alba fruits (MAF) belong to the Moraceae family, which are known to be
effective in treating diabetic, autoimmune, and hormonal diseases owing to its low toxicity …