Independent methylome-wide association studies of schizophrenia detect consistent case–control differences
Methylome-wide association studies (MWASs) are promising complements to sequence
variation studies. We used existing sequencing-based methylation data, which assayed the …
variation studies. We used existing sequencing-based methylation data, which assayed the …
Dopamine and working memory: genetic variation, stress and implications for mental health
K Klaus, K Pennington - Processes of Visuospatial Attention and Working …, 2019 - Springer
At the molecular level, the neurotransmitter dopamine (DA) is a key regulatory component of
executive function in the prefrontal cortex (PFC) and dysfunction in dopaminergic (DAergic) …
executive function in the prefrontal cortex (PFC) and dysfunction in dopaminergic (DAergic) …
Genome-wide methylation analysis of treatment resistant schizophrenia
V De Luca, Z Chaudhary, N Al-Chalabi, J Qian… - Journal of Neural …, 2023 - Springer
Various studies have investigated the relationship between genetic polymorphisms of
antipsychotic drug-metabolizing agents and drug response. DNA methylation is a form of …
antipsychotic drug-metabolizing agents and drug response. DNA methylation is a form of …
[HTML][HTML] SLC38A10 knockout mice display a decreased body weight and an increased risk-taking behavior in the open field test
FA Lindberg, K Nordenankar… - Frontiers in Behavioral …, 2022 - frontiersin.org
The solute carrier 38 family (SLC38) is a family of 11 members. The most common substrate
among these are alanine and glutamine, and members are present in a wide range of …
among these are alanine and glutamine, and members are present in a wide range of …
[HTML][HTML] Using openly accessible resources to strengthen causal inference in epigenetic epidemiology of neurodevelopment and mental health
The recent focus on the role of epigenetic mechanisms in mental health has led to several
studies examining the association of epigenetic processes with psychiatric conditions and …
studies examining the association of epigenetic processes with psychiatric conditions and …
Integrated genome-wide methylation and expression analyses provide predictors of diagnosis and early response to antidepressant in panic disorder
Z Zou, Y Zhang, Y Huang, J Wang, W Min… - Journal of Affective …, 2023 - Elsevier
Background We investigated differentially methylated and expressed genes between panic
disorder (PD) and healthy controls (HCs) to determine whether DNA methylation and …
disorder (PD) and healthy controls (HCs) to determine whether DNA methylation and …
[HTML][HTML] Effects of improved on-farm crop storage on DNA methylation of mothers and their infants: evidence from a randomized controlled trial in Kenya
Background Stress during pregnancy can lead to adverse maternal and infant health
outcomes through epigenetic changes in the hypothalamic–pituitary–adrenal axis. Among …
outcomes through epigenetic changes in the hypothalamic–pituitary–adrenal axis. Among …
[HTML][HTML] Subjective mental health, incidence of depressive symptoms in later life, and the role of epigenetics: results from two longitudinal cohort studies
L Perna, Y Zhang, PR Matias-Garcia, KH Ladwig… - Translational …, 2020 - nature.com
The role of self-perceived general health in predicting morbidity and mortality among older
people is established. The predictive value of self-perceived mental health and of its …
people is established. The predictive value of self-perceived mental health and of its …
Cortical cellular diversity and development in schizophrenia
While a definitive understanding of schizophrenia etiology is far from current reality, an
increasing body of evidence implicates perturbations in early development that alter the …
increasing body of evidence implicates perturbations in early development that alter the …
Urine 5MedC, a marker of DNA methylation, in the progression of chronic kidney disease
A Onishi, H Sugiyama, M Kitagawa… - Disease …, 2019 - Wiley Online Library
Background. Alterations in DNA methylation may be involved in disease progression in
patients with chronic kidney disease (CKD). Recent studies have suggested that 5‐methyl …
patients with chronic kidney disease (CKD). Recent studies have suggested that 5‐methyl …