Exosomes are extracellular vesicles secreted by a variety of living cells, which have a
certain degree of natural targeting as nano-carriers. Almost all exosomes released by cells …

Glioblastoma multiforme is the most aggressive malignant tumor of the central nervous
system. Due to the absence of effective pharmacological and surgical treatments, the …

Glioblastomas (GBM) are highly aggressive primary brain tumors. Complex and dynamic
tumor microenvironment (TME) plays a crucial role in the sustained growth, proliferation, and …

CircRNAs are a class of single-stranded RNA molecules with a covalently closed loop
structure and have been characterized by high stability, abundance, conservation, and …

Liquid biopsy represents a minimally invasive procedure that can provide similar information
from body fluids to what is usually obtained from a tissue biopsy sample. Its implementation …

Glioblastoma (GBM) is an immunosuppressive, lethal brain tumor. Despite advances in
molecular understanding and therapies, the clinical benefits have remained limited, and the …

Glioblastoma (GBM) is the most common and most aggressive brain tumour. Prognosis
remains poor, despite the combined treatment of radio-and chemotherapy following surgical …

Simple Summary This paper summarizes the crosstalk between tumor/non-tumor cells and
other elements of the glioblastoma (GB) microenvironment. In tumor pathology, glial cells …

Extracellular vesicles (EVs) are released from nearly all mammalian cells and different EV
populations have been described. Microvesicles represent large EVs (LEVs) released from …

Astrocyte activation plays an important role during disease-induced inflammatory response
in the brain. Exosomes in the brain could be released from bone marrow (BM)-derived stem …