Simple Summary Tumor biomarkers are molecules at genetic or protein level, or certain
evaluable characteristics. These help in perfecting patient management. Over the past …

Thyroid cancer continues to exhibit a rising incidence globally, predominantly affecting
women. Despite stable mortality rates, the unique characteristics of thyroid carcinoma …

Background: Alterations in DNA methylation are stable epigenetic events that can serve as
clinical biomarkers. The aim of this study was to analyze methylation patterns among various …

Accurately distinguishing of papillary thyroid cancer (PTC) from benign nodules, at the same
time, avoiding overdiagnosis is of great significance. In consideration of the role of miRNA in …

Human cancers are heterogenous by their cell composition and origination site. Cancer
metastasis generates the conundrum of the unknown origin of migrated tumor cells. Tracing …

Lymph node metastases are strongly associated with unfavorable prognosis in papillary
thyroid carcinoma (PTC) patients. However, there are few sensitive or specific indicators that …

Simple Summary Thyroid nodules are frequently detected, but the majority of these nodules
are benign. Molecular markers have become useful for diagnosing the minority of thyroid …

Summary Background Cell-free DNA (cfDNA) is being explored as biomarker for non-
invasive diagnosis of cancer. We aimed to establish a cfDNA-based DNA methylation …

Simple Summary Epigenetic alterations are critical for tumor onset and development. DNA
methylation is one of the most studied pathways concerning various types of cancer. A …

Background. Thyroid carcinoma (THCA) is the most frequent endocrine malignancy.
Papillary thyroid carcinoma (PTC) is the major subtype of THCA, accounting for over 80% of …