Initiation of DNA replication in mitochondrial and viral genomes requires unique DNA
sequences and specific proteins whose precise function is not known. Although little is …

Leading experts from all over the world present an overview of the use of enzymes in
industry for:-the production of bulk products, such as glucose, or fructose-food processing …

Industrial uses of enzymes are discussed under the following chapter headings: introduction
(history, enzyme nomenclature and structure, and molecular biology); catalytic activity of …

The viral DNA polymerases, with their probable role in viral DNA replication, point up the
delicate control of DNA replication. Each cellular or viral induced DNA polymerase seems to …

By equilibrium dialysis a disadenosine 5', 5'''-P1, P2-tetraphosphate (Ap4A) binding activity
is shown to be present in mammalian cells. The Ap4A binding activity copurifies with DNA …

The DNA polymerase of early embryos of Drosophila melanogaster has been purified to
near-homogeneity. The purified enzyme gave a single, catalytically active protein band after …

Two species of alpha-polymerase with very similar catalytic properties have been purified to
near homogeneity from a soluble protein fraction of mouse myeloma. Sedimentation …

Background DNA transactions such as replication, repair and recombination require the
concerted action of many proteins either alone or in a complex 1. Nevertheless, in all these …

The DNA polymerase alpha from regenerating rat liver has been purified to near
homogeneity. The most highly purified fraction gave a single stained band on native …

A detailed study of the mechanism of nascent chain elongation and of steady state kinetics
of purified mouse DNA polymerase alpha has been conducted. Polymerization was …