[HTML][HTML] Indole compounds in oncology: therapeutic potential and mechanistic insights
Cancer remains a formidable global health challenge, with current treatment modalities such
as chemotherapy, radiotherapy, surgery, and targeted therapy often hindered by low efficacy …
as chemotherapy, radiotherapy, surgery, and targeted therapy often hindered by low efficacy …
The Past and Future of Angiogenesis as a Target for Cancer Therapy and Prevention
Cancer growth is dependent on angiogenesis, the formation of new blood vessels, which
represents a hallmark of cancer. After this concept was established in the 1970s, inhibition of …
represents a hallmark of cancer. After this concept was established in the 1970s, inhibition of …
Discovery of novel bioactive compounds in Catharanthus roseus exhibiting anti-angiogenic activity against VEGFR-2 TKD for Glioblastoma tumor growth suppression
A Senrung, D Kumar, N Bhardwaj… - Biomedical and …, 2024 - pubs.thesciencein.org
The progression of Glioblastoma (GBM) relies heavily on angiogenesis, the formation of new
blood vessels, facilitated by proangiogenic factors like vascular endothelial growth factor …
blood vessels, facilitated by proangiogenic factors like vascular endothelial growth factor …
Design, synthesis, anti‐cancer, anti‐inflammatory and in silico studies of 3‐substituted‐2‐oxindole derivatives
This study focuses on the design and multistep synthesis of diverse structural and functional
3‐substituted‐2‐oxindole derivatives aimed at being dual‐active molecules with anti‐cancer …
3‐substituted‐2‐oxindole derivatives aimed at being dual‐active molecules with anti‐cancer …