[HTML][HTML] Epigenetics of male infertility: the role of DNA methylation
JC Rotondo, C Lanzillotti, C Mazziotta… - Frontiers in Cell and …, 2021 - frontiersin.org
In recent years, a number of studies focused on the role of epigenetics, including DNA
methylation, in spermatogenesis and male infertility. We aimed to provide an overview of the …
methylation, in spermatogenesis and male infertility. We aimed to provide an overview of the …
[HTML][HTML] SARS-CoV-2 infection: new molecular, phylogenetic, and pathogenetic insights. Efficacy of current vaccines and the potential risk of variants
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is a newly discovered
coronavirus responsible for the coronavirus disease 2019 (COVID-19) pandemic. COVID-19 …
coronavirus responsible for the coronavirus disease 2019 (COVID-19) pandemic. COVID-19 …
[HTML][HTML] Advanced molecular and immunological diagnostic methods to detect SARS-CoV-2 infection
Simple Summary COVID-19 emerged in late 2019 in China and rapidly spread across the
globe. After 2 years, numerous advances have been made. First of all, the preventive …
globe. After 2 years, numerous advances have been made. First of all, the preventive …
[HTML][HTML] Cancer biology and molecular genetics of A3 adenosine receptor
C Mazziotta, JC Rotondo, C Lanzillotti, G Campione… - Oncogene, 2022 - nature.com
Abstract A3 adenosine receptor (A3AR) is a cell membrane protein, which has been found to
be overexpressed in a large number of cancer types. This receptor plays an important role in …
be overexpressed in a large number of cancer types. This receptor plays an important role in …
[HTML][HTML] DNMT and HDAC inhibition induces immunogenic neoantigens from human endogenous retroviral element-derived transcripts
A Goyal, J Bauer, J Hey, DN Papageorgiou… - Nature …, 2023 - nature.com
Immunotherapies targeting cancer-specific neoantigens have revolutionized the treatment of
cancer patients. Recent evidence suggests that epigenetic therapies synergize with …
cancer patients. Recent evidence suggests that epigenetic therapies synergize with …
[HTML][HTML] Epigenetic dysregulations in merkel cell polyomavirus-driven merkel cell carcinoma
JC Rotondo, C Mazziotta, C Lanzillotti… - International Journal of …, 2021 - mdpi.com
Merkel cell polyomavirus (MCPyV) is a small DNA virus with oncogenic potential. MCPyV is
the causative agent of Merkel Cell Carcinoma (MCC), a rare but aggressive tumor of the …
the causative agent of Merkel Cell Carcinoma (MCC), a rare but aggressive tumor of the …
[HTML][HTML] The role of histone post-translational modifications in merkel cell carcinoma
C Mazziotta, C Lanzillotti, R Gafà, A Touzé… - Frontiers in …, 2022 - frontiersin.org
Merkel Cell Carcinoma (MCC) is a is a rare but highly aggressive form of non–melanoma
skin cancer whose 5-year survival rate is 63%. Merkel cell polyomavirus (MCPyV), a small …
skin cancer whose 5-year survival rate is 63%. Merkel cell polyomavirus (MCPyV), a small …
[HTML][HTML] MicroRNAs modulate signaling pathways in osteogenic differentiation of mesenchymal stem cells
C Mazziotta, C Lanzillotti, MR Iaquinta… - International journal of …, 2021 - mdpi.com
Mesenchymal stem cells (MSCs) have been identified in many adult tissues and they have
been closely studied in recent years, especially in view of their potential use for treating …
been closely studied in recent years, especially in view of their potential use for treating …
Mechanisms of response and resistance to combined decitabine and ipilimumab for advanced myeloid disease
The challenge of eradicating leukemia in patients with acute myelogenous leukemia (AML)
after initial cytoreduction has motivated modern efforts to combine synergistic active …
after initial cytoreduction has motivated modern efforts to combine synergistic active …
[HTML][HTML] Cell-free DNA 5-hydroxymethylcytosine is an emerging marker of acute myeloid leukemia
J Shao, S Wang, D West-Szymanski, J Karpus… - Scientific Reports, 2022 - nature.com
Abstract Aberrant changes in 5-hydroxymethylcytosine (5hmC) are a unique epigenetic
feature in many cancers including acute myeloid leukemia (AML). However, genome-wide …
feature in many cancers including acute myeloid leukemia (AML). However, genome-wide …