Osteosarcoma (OS) is the most frequent primary bone cancer in children and adolescents
and the third most frequent in adults. Many inherited germline mutations are responsible for …

Osteosarcoma (OS) is one of the most common bone cancers that constantly affects
children, teenagers, and young adults. Numerous epigenetic elements, such as miRNAs …

Osteosarcoma is the most common primary malignant bone tumor in children and young
adults. The standard-of-care curative treatment for osteosarcoma utilizes doxorubicin …

Background Musculoskeletal disorder (MSD) are a class of inflammatory and degener‐ative
diseases, but the precise molecular mechanisms are still poorly understood. Noncoding …

YAP and TAZ are intracellular messengers communicating multiple interacting extracellular
biophysical and biochemical cues to the transcription apparatus in the nucleus and back to …

Osteosarcoma is one of the most prevalent primary bone tumors with a high metastatic and
recurrence rate with poor prognosis. MiRNAs are short and non-coding RNAs that could …

Chemoresistance is the main obstacle in osteosarcoma (OS) treatment; however, the
underlying mechanism remains unclear. In this study, it is discovered that DDRGK domain …

Bone is the most frequent site of breast cancer and prostate cancer metastasis, and one of
the most common sites of metastasis for many solid tumors. Once cancer cells colonize in …

Cancer-induced bone degradation is part of the pathological process associated with both
primary bone cancers, such as osteosarcoma, and bone metastases originating from, eg …

Osteosarcoma (OS) is a common and malignant form of bone cancer, which affects children
and young adults. OS is identified by osteogenic differentiation and metastasis. However …