Translational models of addiction phenotypes to advance addiction pharmacotherapy

LA Ray, SJ Nieto, EN Grodin - … of the New York Academy of …, 2023 - Wiley Online Library
Alcohol and substance use disorders are heterogeneous conditions with limited effective
treatment options. While there have been prior attempts to classify addiction subtypes, they …

[HTML][HTML] Proof-of-concept trial of goal management training+ to improve executive functions and treatment outcomes in methamphetamine use disorder

AC Anderson, AH Robinson, E Giddens… - Drug and Alcohol …, 2023 - Elsevier
Background Deficits in executive function are common in methamphetamine use disorder
(MUD), likely contributing to difficulties in sustained treatment success. Cognitive …

Effectiveness of Emotion-Regulation Interventions on Substance Misuse and Emotion Regulation Outcomes in Individuals with Substance Dependence: A Systematic …

S Peri, GK Neppala, RB Shaik, MA Parvaz - Current Addiction Reports, 2024 - Springer
Abstract Purpose of Review Substance dependence across multiple substances is
consistently associated with emotion dysregulation. In the last two decades, emotion …

[HTML][HTML] Ketogenic diet reduces a neurobiological craving signature in inpatients with alcohol use disorder

CE Wiers, P Manza, GJ Wang, ND Volkow - Frontiers in Nutrition, 2024 - frontiersin.org
Background and Aims: Increasing evidence suggests that a ketogenic (high-fat, low-
carbohydrate) diet (KD) intervention reduces alcohol withdrawal severity and alcohol …

Tobacco Images Choice and Its Association with Craving and Dependence in People who Smoke Cigarettes

M Solinas, C Chauvet… - Nicotine and …, 2024 - academic.oup.com
Introduction Increased salience of drug-related cues over non-drug reinforcers can drive
drug use and contribute to tobacco use disorder (TUD). An important scientific and clinical …

[PDF][PDF] Robust identification of a neuromarker of methamphetamine craving

MA Parvaz, T Bel-Bahar - Cell Reports Medicine, 2024 - cell.com
In the January issue of Cell Reports Medicine, Tian et al. 1 apply high-density 128-channel
resting-state electroencephalography (EEG) to examine the neurophysiological …

Ketogenic diet reduces a neurobiological craving signature in alcohol use disorder

C Wiers, P Manza, GJ Wang, ND Volkow - medRxiv, 2023 - medrxiv.org
Background and Aims: Increasing evidence suggests that a ketogenic (high-fat, low-
carbohydrate) diet intervention reduces alcohol withdrawal severity and alcohol craving in …

[HTML][HTML] Speak and you shall predict: speech at initial cocaine abstinence as a biomarker of long-term drug use behavior

C Agurto, G Cecchi, S King, EK Eyigoz, MA Parvaz… - bioRxiv, 2023 - ncbi.nlm.nih.gov
Objective: To determine if baseline linguistic markers in natural speech, as compared to non-
speech clinical and demographic measures, can predict drug use severity measures at …

Theta Burst Stimulation of the Hyperdirect Pathway Boosts Inhibitory Control and Reduces Craving and Smoking in Nicotine-Dependent Adults

TE Baker, D Robles - Biological Psychiatry: Cognitive …, 2023 - biologicalpsychiatrycnni.org
Extensive empirical and theoretical work has delineated common and separable
neurocognitive impairments across multiple substance use disorders (1). Such …

Will the promise of translational neuropsychopharmacology research ever deliver? The lion's roar; the kitten's purr

JF McGinty, V Arango, KT Brady, SD Comer… - … —Digital Psychiatry and …, 2024 - nature.com
The gap between neuropsychopharmacology research claims (the lion's roar) and effective
treatments for neuropsychiatric disorders (the kitten's purr) persists. However, a pattern of …