Colorectal cancer (CRC) is a leading cause of cancer death worldwide. It includes different
subtypes that differ in their clinical and prognostic features. In the past decade, in addition to …

In light of the high incidence and mortality rates of cancer, early and accurate diagnosis is an
important priority for assigning optimal treatment for each individual with suspected illness …

Background Colorectal cancer (CRC) screening can effectively reduce disease-related
mortality by detecting CRC at earlier stages. We have previously demonstrated that the …

Aberrant methylation is one of the most frequent epigenetic alterations that can contribute to
tumor formation. Cell-free DNA can originate from tumor tissue; therefore, the evaluation of …

Background Colorectal cancer (CRC) screening is the most efficient strategy to reduce
disease-related mortality. Frequent aberrant DNA methylation is known to occur in selected …

Colorectal cancer (CRC) is frequently diagnosed at an advanced stage of the disease, the
pathogenesis of which is influenced by genetic and epigenetic events. Circulating tumor …

Background Detection of aberrant methylated DNA in the stool is an effective early
screening method for colorectal cancer (CRC). Previously, reporters identified that syndecan …

Abstract Background Differential microRNA (miRNA) expression profiles in plasma or serum
were identified, providing foundation for studying their potentially diagnostic role in …

Colorectal cancer (CRC) is a leading cause of morbidity and mortality worldwide and its
incidence increases with age. The proportion of older adults in the United States continues …

Background Prevention and early detection of colorectal cancer (CRC) is a global priority,
with many countries conducting population-based CRC screening programs. Although …