Mammalian DNA methylome dynamics: mechanisms, functions and new frontiers
ABSTRACT DNA methylation is a highly conserved epigenetic modification that plays
essential roles in mammalian gene regulation, genome stability and development. Despite …
essential roles in mammalian gene regulation, genome stability and development. Despite …
CelFiE-ISH: a probabilistic model for multi-cell type deconvolution from single-molecule DNA methylation haplotypes
Deconvolution methods infer quantitative cell type estimates from bulk measurement of
mixed samples including blood and tissue. DNA methylation sequencing measures multiple …
mixed samples including blood and tissue. DNA methylation sequencing measures multiple …
Extremely low-frequency electromagnetic field exposure alters DNA methylation levels in the endometrium of pigs during the peri-implantation period
PJ Wydorski, W Kozlowska… - Reproduction …, 2023 - CSIRO Publishing
Context Extremely low-frequency electromagnetic field (ELF-EMF) emission is increasing
due to substantial technological progress. The results of previous research provided …
due to substantial technological progress. The results of previous research provided …
Methyl‐supplemented nutrition delays the development of autoimmune disease in pristane‐induced murine lupus
S Bradyanova, I Manoylov, G Boneva… - …, 2024 - Wiley Online Library
The aetiology and progression of systemic lupus erythematosus (SLE) resulted from a
complex sequence of events generated both from genetic and epigenetic processes. In the …
complex sequence of events generated both from genetic and epigenetic processes. In the …
Liver‐specific deletion of de novo DNA methyltransferases protects against glucose intolerance in high‐fat diet‐fed male mice
S Yao, K Prates, A Freydenzon, G Assante… - The FASEB …, 2024 - Wiley Online Library
Alterations to gene transcription and DNA methylation are a feature of many liver diseases
including fatty liver disease and liver cancer. However, it is unclear whether the DNA …
including fatty liver disease and liver cancer. However, it is unclear whether the DNA …
In situ sequence-specific visualization of single methylated cytosine on tissue sections using ICON probe and rolling-circle amplification
S Kitazawa, R Haraguchi, Y Takaoka… - Histochemistry and Cell …, 2023 - Springer
Since epigenetic modifications differ from cell to cell, detecting the DNA methylation status of
individual cells is requisite. Therefore, it is important to conduct “morphology-based …
individual cells is requisite. Therefore, it is important to conduct “morphology-based …
Atlas of imprinted and allele-specific DNA methylation in the human body
J Rosenski, A Peretz, J Magenheim, N Loyfer… - bioRxiv, 2024 - biorxiv.org
Allele-specific DNA methylation, determined genetically or epigenetically, is involved in
gene regulation and underlies multiple pathologies. Yet, our knowledge of this phenomenon …
gene regulation and underlies multiple pathologies. Yet, our knowledge of this phenomenon …
DNA Methylation as an Epigenetic Mechanism of Anticipation
M Szyf - Epigenetics and Anticipation, 2022 - Springer
The genomes of species across the evolutionary landscape contain in addition to the
genetic information encoded in the 4 letters of the DNA minor bases, methylated adenines …
genetic information encoded in the 4 letters of the DNA minor bases, methylated adenines …
Investigating the Molecular Basis of Adult Neurogenesis: Single-Cell Multi-Omics Unveils DNA Methylation as a Key Regulator of Astrocyte Stemness
LPM Kremer - 2023 - archiv.ub.uni-heidelberg.de
The ventricular-subventricular zone (vSVZ) of adult mammalian brains harbors specialized
astrocytes, called adult neural stem cells (NSCs), which are capable of generating both …
astrocytes, called adult neural stem cells (NSCs), which are capable of generating both …
Elucidating Gene Regulatory Roles of DNA Modifications and Active DNA Demethylation Pathways
AT Wei - 2023 - search.proquest.com
DNA methylation is an epigenetic modification with profound roles in transcription, genomic
stability, and development. The discovery that Ten-Eleven Translocation (TET) proteins …
stability, and development. The discovery that Ten-Eleven Translocation (TET) proteins …