[HTML][HTML] Treatment of overdose in the synthetic opioid era

P Skolnick - Pharmacology & therapeutics, 2022 - Elsevier
Overdose deaths are often viewed as the leading edge of the opioid epidemic which has
gripped the United States over the past two decades (Skolnick, 2018a). This emphasis is …

A review: fentanyl and non-pharmaceutical fentanyls

J Suzuki, S El-Haddad - Drug and alcohol dependence, 2017 - Elsevier
Background Fentanyl and non-pharmaceutical fentanyls (NPFs) have been responsible for
numerous outbreaks of overdoses all over the United States since the 1970s. However …

[PDF][PDF] Pharmacogenomics of GPCR drug targets

AS Hauser, S Chavali, I Masuho, LJ Jahn… - Cell, 2018 - cell.com
Natural genetic variation in the human genome is a cause of individual differences in
responses to medications and is an underappreciated burden on public health. Although …

Opioid abuse in the United States and Department of Health and Human Services actions to address opioid-drug-related overdoses and deaths

US Department of Health and Human … - Journal of Pain & …, 2015 - Taylor & Francis
ABSTRACT On March 26, 2015, the Office of the Assistant Secretary for Planning and
Evaluation of the US Department of Health and Human Services (HSS) published an online …

Pharmaceutically active compounds in aqueous environment: a status, toxicity and insights of remediation

A Majumder, B Gupta, AK Gupta - Environmental research, 2019 - Elsevier
Pharmaceutically active compounds (PhACs) have pernicious effects on all kinds of life
forms because of their toxicological effects and are found profoundly in various wastewater …

A systematic review of community opioid overdose prevention and naloxone distribution programs

AK Clark, CM Wilder, EL Winstanley - Journal of addiction …, 2014 - journals.lww.com
Community-based opioid overdose prevention programs (OOPPs) that include the
distribution of naloxone have increased in response to alarmingly high overdose rates in …

Opioid-associated out-of-hospital cardiac arrest: distinctive clinical features and implications for health care and public responses: a scientific statement from the …

C Dezfulian, AM Orkin, BA Maron, J Elmer, S Girotra… - Circulation, 2021 - Am Heart Assoc
Opioid overdose is the leading cause of death for Americans 25 to 64 years of age, and
opioid use disorder affects> 2 million Americans. The epidemiology of opioid-associated out …

[HTML][HTML] Focus: Addiction: Reducing fatal opioid overdose: Prevention, treatment and harm reduction strategies

KF Hawk, FE Vaca, G D'Onofrio - The Yale journal of biology and …, 2015 - ncbi.nlm.nih.gov
The opioid overdose epidemic is a major threat to the public's health, resulting in the
development and implementation of a variety of strategies to reduce fatal overdose [1-3] …

The ASAM national practice guideline for the treatment of opioid use disorder: 2020 focused update

C Cunningham, MJ Edlund, M Fishman, AJ Gordon… - J Addict Med, 2020 - journals.lww.com
Purpose The American Society of Addiction Medicine (ASAM) developed the National
Practice Guideline for the Treatment of Opioid Use Disorder (the Practice Guideline) to …

The opioid epidemic in the United States

RG Wilkerson, HK Kim, TA Windsor… - Emergency Medicine …, 2016 - emed.theclinics.com
The United States is currently experiencing an epidemic of opioid abuse. This article
discusses the history of opioid use for pain management and how epidemiologic data …