Abstract Background and Aims Naloxone access laws (NALs) have been suggested to be
an important strategy to reduce opioid‐related harm. We describe the evolution of NALs …

Opioid overdose and mortality have increased at an alarming rate prompting new public
health initiatives to reduce drug poisoning. One initiative is to expand access to the opioid …

Prevention of Opioid Overdose This review explains harm-reduction strategies for three
groups of patients: those who have not received previous opioid therapy, those receiving …

Abstract Background Overdose Education and Naloxone Distribution (OEND) training for
persons who inject drugs (PWID) underlines the importance of summoning emergency …

Naloxone is a well-established essential medicine for the treatment of life-threatening
heroin/opioid overdose in emergency medicine. Over two decades, the concept of 'take …

Background Poisoning is one of the leading causes of admission to the emergency
department and intensive care unit. A large number of epidemiological changes have …

This widely respected text and practitioner guide, now revised and expanded, provides a
roadmap for effective clinical practice with clients with substance use disorders. Specialists …

We investigated whether morphine and its pro-drug codeine are substrates of the highly
genetically polymorphic organic cation transporter OCT1 and whether OCT1 polymorphisms …

Background Opioid overdose deaths have increased exponentially in the United States.
Bystander response to opioid overdose ideally involves administering naloxone, providing …

Background Drugs acting on μ-opioid receptors (MORs) are widely used as analgesics but
present side effects including life-threatening respiratory depression. MORs are G-protein …