Introduction The adulteration of heroin with non-pharmaceutical fentanyl and other high-
potency opioids is one of the factors contributing to striking increases in overdose deaths. To …

Abstract The United States is currently experiencing a public health crisis of opioid addiction,
which has its genesis in an industry marketing effort that successfully encouraged clinicians …

What is known and objective A large percentage of opioid overdose fatalities involve
fentanyl or one of its legal or illegal analogs (F/FAs). Is there something about the …

Introduction When managing opioid overdose (OD) patients, the optimal naloxone regimen
should rapidly reverse respiratory depression while avoiding opioid withdrawal. Published …

Opioid use disorder has been designated a worsening epidemic with over 100,000 deaths
due to opioid overdoses recorded in 2021 alone. Unintentional deaths due to opioid …

Naloxone administration is an important component of resuscitation attempts by emergency
medical services (EMS) for opioid drug overdoses. However, EMS providers must first …

Abstract Background Extreme Risk Protection Orders (ERPOs) are a relatively new type of
law that are being considered or implemented in many states in the United States …

Objective To develop machine learning models for classifying the severity of opioid
overdose events from clinical data. Materials and methods Opioid overdoses were identified …

Substance use disorders are common, although the prevalence in the inpatient setting is not
well defined. In 2012, it was estimated that 11% of adult hospitalizations involved substance …

Recently, noscapine was reported as anticancer drug. Unlike, colchicine and
podophyllotoxin, noscapine did not depolymerize microtubules even at stoichiometric …