[HTML][HTML] Genome-wide DNA methylomic differences between dorsolateral prefrontal and temporal pole cortices of bipolar disorder
AMC Ho, SJ Winham, SM Armasu, CJ Blacker… - Journal of psychiatric …, 2019 - Elsevier
Dorsolateral prefrontal cortex (DLPFC) and temporal pole (TP) are brain regions that display
abnormalities in bipolar disorder (BD) patients. DNA methylation—an epigenetic mechanism …
abnormalities in bipolar disorder (BD) patients. DNA methylation—an epigenetic mechanism …
[HTML][HTML] Multivariate analysis reveals differentially expressed genes among distinct subtypes of diffuse astrocytic gliomas: diagnostic implications
N González-García, AB Nieto-Librero, AL Vital… - Scientific Reports, 2020 - nature.com
Diagnosis and classification of gliomas mostly relies on histopathology and a few genetic
markers. Here we interrogated microarray gene expression profiles (GEP) of 268 diffuse …
markers. Here we interrogated microarray gene expression profiles (GEP) of 268 diffuse …
Desmoglein 3 contributes to tumorigenicity of pancreatic ductal adenocarcinoma through activating Src–FAK signaling
Y Abula, Y Su, D Tuniyazi, C Yi - Animal Cells and Systems, 2021 - Taylor & Francis
Desmogleins (DSGs), with the ability to link adjacent cells, have been shown to participate in
the development of malignancy. DSG3 was up-regulated in various cancers, including lung …
the development of malignancy. DSG3 was up-regulated in various cancers, including lung …
[HTML][HTML] DNA methylome in pancreatic cancer identified novel promoter hyper-methylation in NPY and FAIM2 genes associated with poor prognosis in Indian patient …
A Chatterjee, A Bararia, D Ganguly, PK Mondal… - Cancer cell …, 2022 - Springer
Background Pancreatic ductal adenocarcinoma (PDAC) is one of the leading cancers
worldwide and has a poor survival, with a 5-year survival rate of only 8.5%. In this study we …
worldwide and has a poor survival, with a 5-year survival rate of only 8.5%. In this study we …
[HTML][HTML] Methylation of the miR‑29b‑3p promoter contributes to angiogenesis, invasion, and migration in pancreatic cancer
L Wang, N Mu, N Qu - Oncology Reports, 2021 - spandidos-publications.com
The aim of the present study was to investigate the effects of microRNA (miR)‑29b‑3p gene
promoter methylation on angiogenesis, invasion, and migration in human pancreatic cancer …
promoter methylation on angiogenesis, invasion, and migration in human pancreatic cancer …
[HTML][HTML] Evaluation of biomarkers, genetic mutations, and epigenetic modifications in early diagnosis of pancreatic cancer
B Rah, MA Banday, GR Bhat, OJ Shah… - World Journal of …, 2021 - ncbi.nlm.nih.gov
BACKGROUND Pancreatic cancer (PC) is one of the deadliest malignancies with an
alarming mortality rate. Despite significant advancement in diagnostics and therapeutics …
alarming mortality rate. Despite significant advancement in diagnostics and therapeutics …
[HTML][HTML] Calcium signaling alterations caused by epigenetic mechanisms in pancreatic cancer: from early markers to prognostic impact
C Gregório, SC Soares-Lima, B Alemar… - Cancers, 2020 - mdpi.com
Pancreatic ductal adenocarcinoma (PDAC) is an aggressive disease with high mortality
rates. PDAC initiation and progression are promoted by genetic and epigenetic …
rates. PDAC initiation and progression are promoted by genetic and epigenetic …
[HTML][HTML] Epigenetic regulation of major histocompatibility complexes in gastrointestinal malignancies and the potential for clinical interception
JE Tovar Perez, S Zhang, W Hodgeman, S Kapoor… - Clinical …, 2024 - Springer
Background Gastrointestinal malignancies encompass a diverse group of cancers that pose
significant challenges to global health. The major histocompatibility complex (MHC) plays a …
significant challenges to global health. The major histocompatibility complex (MHC) plays a …
CA19-9 in combination with methylated HOXA1 and SST is useful to diagnose stage I pancreatic cancer
Y Suehiro, S Suenaga, Y Kunimune, S Yada… - Oncology, 2022 - karger.com
Introduction: We previously developed a novel methylation assay, the combined restriction
digital PCR (CORD) assay, consisting of treatment of DNA with methylation-sensitive …
digital PCR (CORD) assay, consisting of treatment of DNA with methylation-sensitive …
[HTML][HTML] Integration of multimodal data from disparate sources for identifying disease subtypes
Simple Summary The diagnostic and treatment strategies of cancer remain generally
suboptimal resulting in over-diagnosis or under-treatment. Though many attempts on …
suboptimal resulting in over-diagnosis or under-treatment. Though many attempts on …