All cell and tissue types constantly release DNA fragments into human body fluids by various
mechanisms including programmed cell death, accidental cell degradation and active …

Asthma is a complex trait, often associated with atopy. The genetic contribution has been
evidenced by familial occurrence. Genome-wide association studies allowed for associating …

Background The complex composition of different cell types within a tissue can be estimated
by deconvolution of bulk gene expression profiles or with various single-cell sequencing …

Most RNA polymerases can initiate transcription from diverse DNA template sequences with
relatively few outright sequence restraints. Recent reports have demonstrated that failure to …

Epigenetics is a discipline that studies potentially reversible heritable changes in gene
expression with no structural modifications in the DNA sequence. The epigenetic machinery …

Aim. To explore various immune cell‐related causal pathways for primary sclerosing
cholangitis (PSC). Methods. Immune cell‐related pathway association study was conducted …

DNA methylation (5mC) and hydroxymethylation (5hmC) are chemical modifications of
cytosine bases which play a crucial role in epigenetic gene regulation. However, cost, data …

DNA methylation is an important epigenetic mark that plays a vital role in gene expression
and cell differentiation. The average DNA methylation level among a group of cells has been …

ABSTRACT DNA methylation of CpG sites is commonly measured using Illumina Infinium
BeadChip platforms. The Infinium MethylationEPIC array has replaced the Infinium …

Intercellular crosstalk effects between DNA methylation and lncRNA regulation remain
elusive in lung carcinoma epigenetics. We present an application toolkit MetLnc in …