Epigenetic variability (DNA methylation/demethylation, histone modifications, microRNA
regulation) is common in physiological and pathological conditions. Epigenetic alterations …

This review summarizes current knowledge and outlines future directions relevant to
questions concerning environmental epigenetics and the processes that contribute to …

Neuropathic pain is a complex chronic condition characterized by various sensory,
cognitive, and affective symptoms. A large percentage of patients with neuropathic pain are …

Background Autism spectrum disorder (ASD) is a severe neurodevelopmental disorder
characterized by deficits in social communication and restricted, repetitive behaviors …

Recent research has linked early life exposure to selective serotonin reuptake inhibitor
medications (SSRIs) to modifications of social behaviors in children. Serotonin is a key …

Exposure to adverse rearing environments including institutional deprivation and severe
childhood abuse is associated with an increased risk for mental and physical health …

Prenatal stress and poor maternal mental health are associated with adverse offspring
outcomes; however, the biological mechanisms are unknown. Epigenetic modification has …

Background Maternal mood disorders and their treatment during pregnancy may have
effects on the offspring epigenome. We aim to evaluate associations of maternal prenatal …

Serotonin has important roles in the development of the brain and other organs.
Manipulations of synaptic serotonin by drugs such as serotonin reuptake inhibitors (SRI) or …

Background Epigenetic clocks have been suggested to capture one feature of the
complexity between aging and the epigenome. However, little is known about the epigenetic …