A potential area of use for immune checkpoint inhibitors: Targeting bone marrow microenvironment in acute myeloid leukemia

B Aru, C Pehlivanoğlu, Z Dal… - Frontiers in …, 2023 - frontiersin.org
Acute myeloid leukemia (AML) arises from the cells of myeloid lineage and is the most
frequent leukemia type in adulthood accounting for about 80% of all cases. The most …

The potential role of the thymus in immunotherapies for acute myeloid leukemia

C Hino, Y Xu, J Xiao, DJ Baylink, ME Reeves… - Frontiers in …, 2023 - frontiersin.org
Understanding the factors which shape T-lymphocyte immunity is critical for the
development and application of future immunotherapeutic strategies in treating …

Analysis of prognostic biomarker models and immune microenvironment in acute myeloid leukemia by integrative bioinformatics

N Wang - Journal of Cancer Research and Clinical Oncology, 2023 - Springer
Background Acute myeloid leukemia (AML) is a hematological cancer driven on by aberrant
myeloid precursor cell proliferation and differentiation. A prognostic model was created in …

[HTML][HTML] Establishment and validation of a prognostic immune-related lncRNA risk model for acute myeloid leukemia

KY Xie, SZ Chen, Y Wang, ML Zeng… - Translational Cancer …, 2023 - ncbi.nlm.nih.gov
Background Acute myeloid leukemia (AML) is a cancer arising in the bone marrow and is
the most common type of adult leukemia. AML has a poor prognosis, and currently, its …

Pan-cancer analysis reveals potential for synergy between SERPINA1 molecular targeting and macrophage-related immunotherapy

C Fu, Y Miao, X Jiao, J Fu, C Liu, Z Yu, M Wei - 2022 - researchsquare.com
Background The immune response can be modulated by autophagy to alter tumor growth.
SERPINA1 is not only an autophagy-related protein but also a serine protease inhibitor with …

Vitamin D a jeho funkce

C De Brito - 2023 - dspace.cuni.cz
Vitamin D je známý pro svoji úlohu během regulace metabolismu minerálních látek v těle.
Jeho nedostatek je spojen především s onemocněními křivice a osteomalacie, vyznačujícími …

Antigen-armed antibodies (AgAbs) in the treatment of Acute Myeloid Leukemia (AML)

GE Wassmer - 2023 - archiv.ub.uni-heidelberg.de
Acute myeloid leukemia (AML) accounts for 80% of acute leukemia cases in adults and
results from the accumulation of immature malignant myeloid progenitor cells at the expense …