Zebrafish (Danio rerio) is emerging as an increasingly successful model for translational
research on human neurological disorders. In this review, we appraise the high degree of …

In vivo studies represent an essential step in drug development and currently rely largely on
mice, yet limitations of mammalian models motivated the search for complementary …

Copy number variants (CNVs) are major contributors to genetic disorders. We have
dissected a region of the 16p11. 2 chromosome—which encompasses 29 genes—that …

Embryo morphogenesis is impacted by dynamic changes in tissue material properties,
which have been proposed to occur via processes akin to phase transitions (PTs). Here, we …

The zebrafish (Danio rerio) is now the pre-eminent vertebrate model system for clarification
of the roles of specific genes and signaling pathways in development. The zebrafish …

Zebrafish (Danio rerio) have emerged as a promising model organism to study
development, toxicology, pharmacology, and neuroscience, among other areas. Despite the …

Neurodegeneration is a major cause of Alzheimer's, Parkinson's, Huntington's, multiple and
amyotrophic lateral sclerosis, pontocerebellar hypoplasia, dementia and other related brain …

There is growing interest in zebrafish as a model organism in behavioral pharmacology
research. Several anxiety behaviors have been characterized in zebrafish, but the effect of …

▪ Abstract Genetic screens in Drosophila melanogaster, Caenorhabditis elegans, and Danio
rerio clarified the logic of metazoan development by revealing critical unitary steps and …

Heartbeat measurement is important in assesssing cardiac function because variations in
heart rhythm can be the cause as well as an effect of hidden pathological heart conditions …