Extracellular vesicles (EV) are lipid-bilayer enclosed vesicles in submicron size that are
released from cells. A variety of molecules, including proteins, DNA fragments, RNAs, lipids …

Antiviral drugs have traditionally been developed by directly targeting essential viral
components. However, this strategy often fails due to the rapid generation of drug-resistant …

Transcriptional regulation, which integrates chromatin accessibility, transcription factors and
epigenetic modifications, is crucial for establishing and maintaining cell identity. The …

Genomic instability can initiate cancer, augment progression, and influence the overall
prognosis of the affected patient. Genomic instability arises from many different pathways …

DNA methylation is a crucial epigenetic modification of the genome that is involved in
regulating many cellular processes. These include embryonic development, transcription …

Osteoclasts are multinucleated cells of monocyte/macrophage origin that degrade bone
matrix. The differentiation of osteoclasts is dependent on a tumor necrosis factor (TNF) family …

We describe a large-scale random approach termed reduced representation bisulfite
sequencing (RRBS) for analyzing and comparing genomic methylation patterns. BglII …

DNA methylation is an important regulator of gene transcription, and its role in
carcinogenesis has been a topic of considerable interest in the last few years. Alterations in …

Cadmium (Cd) is a highly toxic heavy metal and has spread widely in the environment in
recent decades. This review summarizes current knowledge about Cd contamination of leafy …

The incidence of obesity and overweight has reached epidemic levels in the United States
and developed countries worldwide. Even more alarming is the increasing prevalence of …