Physiological basis for xenotransplantation from genetically modified pigs to humans

L Peterson, MH Yacoub, D Ayares… - Physiological …, 2024 - journals.physiology.org
The collective efforts of scientists over multiple decades have led to advancements in
molecular and cellular biology-based technologies including genetic engineering and …

Transgressive and parental dominant gene expression and cytosine methylation during seed development in Brassica napus hybrids

M Orantes-Bonilla, H Wang, HT Lee, AA Golicz… - Theoretical and Applied …, 2023 - Springer
Key message Transcriptomic and epigenomic profiling of gene expression and small RNAs
during seed and seedling development reveals expression and methylation dominance …

Epigenetic aspects and prospects in autoimmune hepatitis

AJ Czaja - Frontiers in immunology, 2022 - frontiersin.org
The observed risk of autoimmune hepatitis exceeds its genetic risk, and epigenetic factors
that alter gene expression without changing nucleotide sequence may help explain the …

[HTML][HTML] Self-empowerment of life through RNA networks, cells and viruses

L Villarreal, G Witzany - F1000Research, 2023 - ncbi.nlm.nih.gov
Our understanding of the key players in evolution and of the development of all organisms in
all domains of life has been aided by current knowledge about RNA stem-loop groups, their …

Cannabis and paternal epigenetic inheritance

F Mazzeo, R Meccariello - … Journal of Environmental Research and Public …, 2023 - mdpi.com
Cannabis is the most widely used illicit drug in Western counties and its abuse is particularly
high in male adolescents and young adults. Its main psychotropic component, the …

Haplotype-resolved 3D chromatin architecture of the hybrid pig

Y Lin, J Li, Y Gu, L Jin, J Bai, J Zhang, Y Wang… - Genome …, 2024 - genome.cshlp.org
In diploid mammals, allele-specific three-dimensional (3D) genome architecture may lead to
imbalanced gene expression. Through ultradeep in situ Hi-C sequencing of three …

Cellular nanomechanics derived from pattern-dependent focal adhesion and cytoskeleton to balance gene transfection of malignant osteosarcoma

Y Wang, N Wang, Y Yang, Y Chen, Z Zhang - Journal of …, 2022 - Springer
Gene transfection was supposed to be the most promising technology to overcome the vast
majority of diseases and it has been popularly reported in clinical applications of gene …

Sperm RNA-mediated epigenetic inheritance in mammals: challenges and opportunities

Q Chen - Reproduction, Fertility and Development, 2022 - CSIRO Publishing
Emerging evidence now shows that in addition to delivering a haploid DNA, the mammalian
sperm also carry various types of RNAs that respond to the paternal environment, which can …

DNA methylation mediates overgrazing-induced clonal transgenerational plasticity

J Yin, W Ren, EL Fry, S Sun, H Han, F Guo - Science of the Total …, 2023 - Elsevier
Overgrazing generally induces dwarfism in grassland plants, and these phenotypic traits
could be transmitted to clonal offspring even when overgrazing is excluded. However, the …

Intergenerational consequences of adolescent morphine exposure on learning and memory

V Alipour, A Shojaei, M Rezaei, J Mirnajafi-Zadeh… - Neuroscience …, 2023 - Elsevier
Drug addiction is a worldwide social and medical disorder. More than 50 percent of drug
abusers start their substance abuse in adolescence between the ages of 15–19 …