[HTML][HTML] Biomarkers for detecting colorectal cancer non-invasively: DNA, RNA or proteins?

A Loktionov - World journal of gastrointestinal oncology, 2020 - ncbi.nlm.nih.gov
Colorectal cancer (CRC) is a global problem affecting millions of people worldwide. This
disease is unique because of its slow progress that makes it preventable and often curable …

[HTML][HTML] Epigenetic landscape of liquid biopsy in colorectal cancer

A Rodriguez-Casanova, N Costa-Fraga… - Frontiers in Cell and …, 2021 - frontiersin.org
Colorectal cancer (CRC) is one of the most common malignancies and is a major cause of
cancer-related deaths worldwide. Thus, there is a clinical need to improve early detection of …

miR-137 is a tumor suppressor in endometrial cancer and is repressed by DNA hypermethylation

W Zhang, JH Chen, T Shan… - Laboratory …, 2018 - nature.com
Endometrial cancer is the most common gynecological cancer in the United States. We
wanted to identify epigenetic aberrations involving microRNAs (miRNAs), whose genes …

[HTML][HTML] The role of microRNAs in development of colitis-associated colorectal cancer

M Bocchetti, MG Ferraro, F Ricciardiello… - International Journal of …, 2021 - mdpi.com
Colorectal cancer (CRC) is the third most deadly cancer worldwide, and inflammatory bowel
disease (IBD) is one of the critical factors in CRC carcinogenesis. IBD is responsible for an …

[HTML][HTML] Epigenetic regulation of MicroRNA clusters and families during tumor development

J Gregorova, P Vychytilova-Faltejskova, S Sevcikova - Cancers, 2021 - mdpi.com
Simple Summary In this review, the history of RNA interference discovery and current
knowledge about microRNA biogenesis and post-transcriptional regulation of gene …

[HTML][HTML] Relevance of microRNAs as potential diagnostic and prognostic markers in colorectal cancer

G Hibner, M Kimsa-Furdzik, T Francuz - International Journal of Molecular …, 2018 - mdpi.com
Colorectal cancer (CRC) is currently the third and the second most common cancer in men
and in women, respectively. Every year, more than one million new CRC cases and more …

A panel of methylated microRNA biomarkers for identifying high-risk patients with ulcerative colitis-associated colorectal cancer

Y Toiyama, Y Okugawa, K Tanaka, T Araki, K Uchida… - Gastroenterology, 2017 - Elsevier
Background & Aims Methylation of specific microRNAs (miRNAs) often occurs in an age-
dependent manner, as a field defect in some instances, and may be an early event in colitis …

[HTML][HTML] Gene promoter and exon DNA methylation changes in colon cancer development–mRNA expression and tumor mutation alterations

B Molnár, O Galamb, B Péterfia, B Wichmann, I Csabai… - BMC cancer, 2018 - Springer
Background DNA mutations occur randomly and sporadically in growth-related genes,
mostly on cytosines. Demethylation of cytosines may lead to genetic instability through …

[HTML][HTML] MicroRNA as epigenetic modifiers in endometrial cancer: a systematic review

A Favier, G Rocher, AK Larsen, R Delangle, C Uzan… - Cancers, 2021 - mdpi.com
Simple Summary Endometrial cancer (EC) is the 2nd most common gynecologic cancer
worldwide. MicroRNAs (miRNAs) are small noncoding RNAs that contribute to epigenetic …

[HTML][HTML] Aberrant DNA methylation of PAX1, SOX1 and ZNF582 genes as potential biomarkers for esophageal squamous cell carcinoma

L Tang, YL Liou, ZR Wan, J Tang, Y Zhou… - Biomedicine & …, 2019 - Elsevier
Background Esophageal squamous cell carcinoma (ESCC) is a highly invasive malignant
tumor and the majority of patients have advanced stage of ESCC at diagnosis with poor …