Background: Tranexamic acid (TXA) is an antifibrinolytic drug that has been shown to be
effective in reducing blood loss and the need for transfusions after several orthopaedic …

Objective To compare the efficacy and safety of the combined application of both
intravenous and topical tranexamic acid versus the single use of either application in …

Background Tranexamic acid (TXA) reduces perioperative blood loss in total hip arthroplasty
(THA). Methods In our randomized control trial, 139 patients were enrolled and received 2 g …

Purpose This comprehensive review was conducted to assess the effects of tranexamic acid
(TXA) on blood loss, venous thromboembolism (VTE) risk, and wound complications …

Background: Revision hip arthroplasty poses several challenges, including the management
of perioperative blood loss. Recent studies have validated the use of tranexamic acid in …

Purpose To perform a systematic review and meta-analysis of randomized clinical trials
(RCTs) investigating the efficacy and safety of topical tranexamic acid (TXA) to prevent …

Antifibrinolytics, particularly tranexamic acid (TXA), are agents used to reduce bleeding. TXA
is a synthetic reversible competitive inhibitor to the lysine receptor found on plasminogen. By …

Background Lack of evidence contributes to unnecessary variation in treatment costs and
outcomes. This study aimed to identify from interventions historically used for total knee or …

Convulsions are a neurological illness that has complexity. In clinical treatment, drug-
induced convulsions appear from time to time. Drug-induced convulsions often begin as …

Intraoperative bleeding is controlled using standard surgical techniques (eg, electrocautery,
vessel ligation, suturing). Using these techniques, blood loss is minimal, with most routine …